Methodological Issues and Laser Speckle Contrast Imaging

NCT ID: NCT01664572

Last Updated: 2016-06-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

75 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-06-30

Study Completion Date

2016-03-31

Brief Summary

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Microcirculation, especially skin microcirculation, is a window towards systemic vascular function in magnitude and underlying mechanisms. Different techniques have been developed to assess the microcirculation. Among these techniques, laser technology is used to perform non-invasive microvascular assessments. Although this technique is widely used, different methodological issues remain. This study aims at defining the way to use lasers for clinical use.

Detailed Description

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Conditions

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Microvascular Function

Study Design

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Study Time Perspective

PROSPECTIVE

Study Groups

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Healthy subjects

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* age \> 18years old
* subject without any known cardiovascular disease

Exclusion Criteria

* pregnancy
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University Hospital, Angers

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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University Hospital

Angers, , France

Site Status

Countries

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France

References

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Omarjee L, Signolet I, Humeau-Heutier A, Martin L, Henrion D, Abraham P. Optimisation of movement detection and artifact removal during laser speckle contrast imaging. Microvasc Res. 2015 Jan;97:75-80. doi: 10.1016/j.mvr.2014.09.005. Epub 2014 Sep 28.

Reference Type DERIVED
PMID: 25261716 (View on PubMed)

Puissant C, Abraham P, Durand S, Humeau-Heurtier A, Faure S, Leftheriotis G, Mahe G. Assessment of endothelial function by acetylcholine iontophoresis: impact of inter-electrode distance and electrical cutaneous resistance. Microvasc Res. 2014 May;93:114-8. doi: 10.1016/j.mvr.2014.04.001. Epub 2014 Apr 13.

Reference Type DERIVED
PMID: 24735977 (View on PubMed)

Puissant C, Abraham P, Durand S, Humeau-Heurtier A, Faure S, Leftheriotis G, Rousseau P, Mahe G. Reproducibility of non-invasive assessment of skin endothelial function using laser Doppler flowmetry and laser speckle contrast imaging. PLoS One. 2013 Apr 19;8(4):e61320. doi: 10.1371/journal.pone.0061320. Print 2013.

Reference Type DERIVED
PMID: 23620742 (View on PubMed)

Other Identifiers

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2012A00458-35

Identifier Type: -

Identifier Source: org_study_id

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