Hemorrhoidal Artery Ligation and Rectoanal Repair Versus Stapled Hemorrhoidopexy

NCT ID: NCT01647763

Last Updated: 2023-08-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

84 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-07-31

Study Completion Date

2024-12-31

Brief Summary

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Background:

Hemorrhoids of grade 3 and 4 can be treated either by conventional, rather invasive procedures, like Milligan-Morgan or Ferguson or by modern, less invasive procedures with less postoperative pain. Doppler guided hemorrhoidal artery ligation and stapled hemorrhoidopexy are examples for such modern procedures. Hemorrhoidal artery ligation causes less post operative pain than stapled hemorrhoidopexy, however the former has a higher recurrence rate. Combining hemorrhoidal artery ligation with rectoanal repair should reduce the recurrence rate without increasing the post operative pain.

Hypothesis and aim:

The study tries to prove the assumption that combined hemorrhoidal artery ligation and rectoanal repair cause less pain and have less post operative complications than stapled hemorrhoidopexy.

Detailed Description

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Conditions

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Hemorrhoids

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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HAL/RAR

hemorrhoidal artery ligation with rectoanal repair

Group Type EXPERIMENTAL

Hemorrhoidal artery ligation with rectoanal repair

Intervention Type PROCEDURE

Hemorrhoidal arteries will be detected using an ultrasound Doppler probe. The arteries will be sutured with at least 4 Z-sutures.

In the area with the 3 largest knots a purse string suture will be placed.

Stapled hemorrhoidopexy

procedure for prolapse and hemorrhoids (PPH)

Resection using a circular stapler

Group Type ACTIVE_COMPARATOR

Stapled hemorrhoidopexy

Intervention Type PROCEDURE

A purse string suture will be placed just below the hemorrhoidal cushion. Fixing the suture around the shaft of a circular PPH 03 stapler (Ethicon Endo-Surgery). Hemorrhoids will be removed by firing the stapler. Sufficiency of the stapler line will be examined through a proctoscope. Eventual sources of bleeding will be sutured.

Interventions

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Hemorrhoidal artery ligation with rectoanal repair

Hemorrhoidal arteries will be detected using an ultrasound Doppler probe. The arteries will be sutured with at least 4 Z-sutures.

In the area with the 3 largest knots a purse string suture will be placed.

Intervention Type PROCEDURE

Stapled hemorrhoidopexy

A purse string suture will be placed just below the hemorrhoidal cushion. Fixing the suture around the shaft of a circular PPH 03 stapler (Ethicon Endo-Surgery). Hemorrhoids will be removed by firing the stapler. Sufficiency of the stapler line will be examined through a proctoscope. Eventual sources of bleeding will be sutured.

Intervention Type PROCEDURE

Other Intervention Names

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HAL (hemorrhoidal artery ligation) RAR (rectoanal repair) Longo procedure

Eligibility Criteria

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Inclusion Criteria

* hemorrhoids grade 3
* no active anti-coagulation treatment
* no hemorrhoidal recurrence
* no previous surgery on rectum or anus
* no previous local radiotherapy
* no mental incapacities, good study compliance can be expected
* no severe incontinence (Wexner score \> 12)
* no severe comorbidities
* no inflammatory anal diseases (abscesses, fistulas)
* informed consent

Exclusion Criteria

* patient wish
* inoperability with the assigned intervention, switching to other treatment method
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Cantonal Hospital of St. Gallen

OTHER

Sponsor Role lead

Responsible Party

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Lukas Marti

Leitender Arzt (attending surgeon)

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Lukas Marti, MD

Role: PRINCIPAL_INVESTIGATOR

Cantonal Hospital St. Gallen, Department of Surgery

Locations

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Kantonsspital Rorschach

_Rorschach, , Switzerland

Site Status

Kantonsspital St. Gallen

Sankt Gallen, , Switzerland

Site Status

Countries

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Switzerland

Related Links

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Other Identifiers

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EKSG11/042

Identifier Type: -

Identifier Source: org_study_id

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