Effectiveness of Beclomethasone Dipropionate Nasal Aerosol for Perennial Allergic Rhinitis

NCT ID: NCT01632540

Last Updated: 2014-04-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

824 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-07-31

Study Completion Date

2014-02-28

Brief Summary

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This study will be a prospective observational study of "real world" BDP nasal aerosol users with PAR, with or without seasonal allergic rhinitis (SAR). Subjects will respond to monthly online surveys regarding rhinitis control, concomitant medical conditions, concomitant (non-AR) medications, current AR therapy, and adverse events.

Detailed Description

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Conditions

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Perennial Allergic Rhinitis (PAR)

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Perennial Allergic Rhinitis patients

Beclomethasone Dipropionate (BDP) Nasal Aerosol

Intervention Type DRUG

BDP nasal aerosol 320 mcg/day will be administered to all patients as 2 sprays in each nostril once daily.

Interventions

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Beclomethasone Dipropionate (BDP) Nasal Aerosol

BDP nasal aerosol 320 mcg/day will be administered to all patients as 2 sprays in each nostril once daily.

Intervention Type DRUG

Other Intervention Names

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QNASL

Eligibility Criteria

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Inclusion Criteria

* Male or female
* Age 12 years or greater at time of enrollment
* Diagnosis of PAR for at least one year; and 2)a positive skin prick (ie, epicutaneous) or serum-specific IgE test within the past 2 years to a perennial allergen as appropriate for the location; and 3)PAR symptoms that are consistent with exposure to this allergen for at least one year
* Uncontrolled rhinitis symptoms at the time of assessment as confirmed by a score of 21 or less on the RCAT
* Newly prescribed BDP Nasal Aerosol (within the past 7 days but have not yet used)
* Willing and able to complete surveys in English on a computer with internet access
* Willing and able to provide informed consent prior to entering the study (or parent/caregiver/legal guardian if applicable)

Exclusion Criteria

* Current acute or chronic sinusitis or chronic purulent nasal discharge
* Rhinitis medicamentosa or nasal structural abnormalities (including nasal polyps and clinically significant septal deviation) that significantly interfere with nasal airflow
* Acute upper respiratory infection within the past 14 days
* Used any pressurized metered-dose inhaler INS product (including BDP Nasal Aerosol and Ciclesonide Nasal Aerosol) within the past 90 days
* Used any experimental therapy for AR within the past 30 days
* Any condition which the investigator feels may interfere with the study
Minimum Eligible Age

12 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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United BioSource, LLC

INDUSTRY

Sponsor Role collaborator

Teva Branded Pharmaceutical Products R&D, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Mark Lepore, MD

Role: PRINCIPAL_INVESTIGATOR

Teva Pharmaceutical Industries, Ltd.

Locations

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Teva Investigational Site 024

Little Rock, Alaska, United States

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Teva Investigational Site 028

Phoenix, Arizona, United States

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Teva Investigational Site 003

Encinitas, California, United States

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Teva Investigational Site 042

Fresno, California, United States

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Teva Investigational Site 006

Los Angeles, California, United States

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Teva Investigational Site 017

Orange, California, United States

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Teva Investigational Site 007

Palmdale, California, United States

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Teva Investigational Site 021

Paramount, California, United States

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Teva Investigational Site 040

Redwood City, California, United States

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Teva Investigational Site 014

Tallahassee, Florida, United States

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Teva Investigational Site 010

Tamarac, Florida, United States

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Teva Investigational Site 038

Albany, Georgia, United States

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Teva Investigational Site 031

Lawrenceville, Georgia, United States

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Teva Investigational Site 035

Savannah, Georgia, United States

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Teva Investigational Site 043

Fort Mitchell, Kentucky, United States

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Teva Investigational Site 034

Owensboro, Kentucky, United States

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Teva Investigational Site 033

Mandeville, Louisiana, United States

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Teva Investigational Site 004

Bethesda, Maryland, United States

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Teva Investigational Site 037

Novi, Michigan, United States

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Teva Investigational Site 026

Omaha, Nebraska, United States

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Teva Investigational Site 002

Brick, New Jersey, United States

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Teva Investigational Site 019

Corning, New York, United States

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Teva Investigational Site 018

New York, New York, United States

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Teva Investigational Site 039

Niagara Falls, New York, United States

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Teva Investigational Site 011

High Point, North Carolina, United States

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Teva Investigational Site 027

Winston-Salem, North Carolina, United States

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Teva Investigational Site 030

Winston-Salem, North Carolina, United States

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Teva Investigational Site 013

Toledo, Ohio, United States

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Teva Investigational Site 022

Ashland, Oregon, United States

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Teva Investigational Site 016

Eugene, Oregon, United States

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Teva Investigational Site 032

Havertown, Pennsylvania, United States

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Teva Investigational Site 025

Normal Square, Pennsylvania, United States

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Teva Investigational Site 012

Pittsburgh, Pennsylvania, United States

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Teva Investigational Site 023

Upland, Pennsylvania, United States

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Teva Investigational Site 015

Dallas, Texas, United States

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Teva Investigational Site 029

Dallas, Texas, United States

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Teva Investigational Site 009

Fort Worth, Texas, United States

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Teva Investigational Site 020

Houston, Texas, United States

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Teva Investigational Site 041

San Antonio, Texas, United States

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Teva Investigational Site 044

San Antonio, Texas, United States

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Teva Investigational Site 046

San Antonio, Texas, United States

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Teva Investigational Site 001

Waco, Texas, United States

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Teva Investigational Site 005

Murray, Utah, United States

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Teva Investigational Site 045

Newport News, Virginia, United States

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Teva Investigational Site 008

Puyallup, Washington, United States

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Teva Investigational Site 036

Greenfield, Wisconsin, United States

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Countries

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United States

Other Identifiers

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BDP-AR-401

Identifier Type: -

Identifier Source: org_study_id

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