Trial Outcomes & Findings for Mechanical Ventilation in the Emergency Department: A Prospective Cross-Sectional Study (NCT NCT01628523)

Results Overview

In a prospective cross-sectional study design, we will enroll all patients receiving mechanical ventilation in the ED over a one-month time frame.

Recruitment status

COMPLETED

Target enrollment

219 participants

Primary outcome timeframe

1 month

Results posted on

2020-03-23

Participant milestones
Measure	All ED Patients Requiring Mechanical Ventilation Assessed for mechanical ventilation parameters, predictors of ARDS in the patients without ARDS in the ED (n=204), and outcome differences between all patients with ARDS (n=45) and those not progressing to ARDS (n= 174). These 45 patients includes the 15 patients with ARDS in the ED and the 30 participants with incident ARDS after ED admission.
Overall Study STARTED	219
Overall Study COMPLETED	219
Overall Study NOT COMPLETED	0

Withdrawal data not reported

Mechanical Ventilation in the Emergency Department: A Prospective Cross-Sectional Study

Baseline characteristics by cohort
Measure	Entire Cohort n=219 Participants Characteristics of mechanically ventilated ED patients
Age, Customized age	55.6 years STANDARD_DEVIATION 19.9 • n=5 Participants
Sex: Female, Male Female	91 Participants n=5 Participants
Sex: Female, Male Male	128 Participants n=5 Participants
Race/Ethnicity, Customized white	152 participants n=5 Participants
Race/Ethnicity, Customized black	59 participants n=5 Participants
Race/Ethnicity, Customized other	8 participants n=5 Participants

Timeframe: 1 month

Population: Tidal volume used for the entire cohort

In a prospective cross-sectional study design, we will enroll all patients receiving mechanical ventilation in the ED over a one-month time frame.

Outcome measures
Measure	Entire Cohort n=219 Participants Characteristics of mechanically ventilated ED patients
To Further Characterize ED Mechanical Ventilation	500 mL Interval 450.0 to 520.0

Timeframe: 1 month

Development of ARDS after admission to the hospital

Outcome measures
Measure	Entire Cohort n=204 Participants Characteristics of mechanically ventilated ED patients
The Incidence of ARDS in Mechanically Ventilated Emergency Department Patients, and Risk Factors Associated With Progression to ARDS	30 participants

Serious events: 0 serious events

Other events: 0 other events

Deaths: 72 deaths

Adverse event data not reported

Adverse event data not reported

Washington University in St. Louis

Phone: 3147475368