Bioequivalence of Two Formulations of Biphasic Insulin Aspart 50 in Japanese Subjects

NCT ID: NCT01620437

Last Updated: 2017-02-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2003-11-29

Study Completion Date

2003-12-30

Brief Summary

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This trial is conducted in Japan. The aim of this trial is to investigate the bioequivalence of two formulations of biphasic insulin aspart 50 (NN-X14Mix50) in healthy Japanese subjects.

Detailed Description

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Conditions

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Diabetes Healthy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Formulation A

Group Type EXPERIMENTAL

biphasic insulin aspart 50

Intervention Type DRUG

A single dose administrated subcutaneously (s.c., under the skin) on two separate dosing visits. A wash-out period of 6-21 days will take place between dosing visits

Formulation B

Group Type EXPERIMENTAL

biphasic insulin aspart 50

Intervention Type DRUG

A single dose administrated subcutaneously (s.c., under the skin) on two separate dosing visits. A wash-out period of 6-21 days will take place between dosing visits

Interventions

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biphasic insulin aspart 50

A single dose administrated subcutaneously (s.c., under the skin) on two separate dosing visits. A wash-out period of 6-21 days will take place between dosing visits

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* BMI (body mass index) between 19-29 kg/m\^2 (both inclusive)
* Fasting blood glucose between 3.8-6.0 mmol/L (both inclusive)
* Non-smokers

Exclusion Criteria

* Subjects with a first-degree relative with diabetes mellitus
* Subjects smoke 5 cigarettes or more per day
Minimum Eligible Age

20 Years

Maximum Eligible Age

50 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Novo Nordisk A/S

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Global Clinical Registry (GCR, 1452)

Role: STUDY_DIRECTOR

Novo Nordisk A/S

Locations

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Novo Nordisk Investigational Site

Tokyo, , Japan

Site Status

Countries

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Japan

Related Links

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http://novonordisk-trials.com

Clinical Trials at Novo Nordisk

Other Identifiers

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BIASP-1581

Identifier Type: -

Identifier Source: org_study_id

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