Clinical Evaluation of a Daily Disposable Contact Lens in Symptomatic Weekly/Monthly Lens Wearers

NCT ID: NCT01614600

Last Updated: 2013-12-04

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

88 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-06-30

Study Completion Date

2012-09-30

Brief Summary

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The purpose of this study was to evaluate the reduction of contact lens-related dryness symptoms when symptomatic weekly/monthly contact lens wearers were switched to DAILIES® AquaComfort Plus® lenses for a two-week period using composite scores on the Contact Lens Dry Eye Questionnaire (CLDEQ).

Detailed Description

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Conditions

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Dry Eye Syndrome Myopia

Keywords

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contact lens dry eye syndrome symptomatic daily disposable myopia

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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DAILIES® AquaComfort Plus®

Nelfilcon A contact lenses worn bilaterally on a daily wear, daily disposable basis for 2 weeks

Group Type EXPERIMENTAL

Nelfilcon A contact lenses

Intervention Type DEVICE

Commercially marketed hydrogel contact lenses for daily wear, daily disposable use

Interventions

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Nelfilcon A contact lenses

Commercially marketed hydrogel contact lenses for daily wear, daily disposable use

Intervention Type DEVICE

Other Intervention Names

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DAILIES® AquaComfort Plus®

Eligibility Criteria

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Inclusion Criteria

* Currently wearing weekly/monthly, silicone hydrogel or traditional hydrogel soft contact lenses at least 8 hours per day and 5 days a week during the past 6 months.
* Identified as symptomatic using a baseline screening questionnaire.
* Requires vision correction in both eyes with a contact lens prescription as follows: sphere powers between -0.50 and -10.00 diopter (D) and cylinder powers \</= 0.75D and no ADD correction.
* Able to achieve visual acuity (VA) of at least 6/7.5 in each eye with study lenses in the available parameters.
* Willing to wear study lenses for at least 8 hours/day and at least 5 days/week and discard the lenses at the end of the day and replace lenses every day with a new fresh pair.
* Willing and able to follow instructions and maintain the appointment schedule.

Exclusion Criteria

* Neophytes and current wearers of daily disposable contact lenses.
* Requires monovision correction.
* Any systemic or ocular disease or disorder (refractive disorder allowed) complicating factors or structural abnormality that would negatively affect the conduct or outcome of the study.
* A history of ocular surgery/trauma within the last 6 months.
* Unwilling to discontinue mechanical eyelid therapy or eyelid scrubs within 14 days of enrollment and continuing during the study.
* Participation in any other ophthalmic drug or device clinical trial within 30 days of enrollment.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Alcon Research

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jami Kern, MBA, PhD

Role: STUDY_DIRECTOR

Alcon Research

Countries

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United States

Other Identifiers

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A00849

Identifier Type: -

Identifier Source: org_study_id