A Multi-center, Prospective, Randomized Study With PriMatrix and PriMatrix Ag for the Treatment of Venous Leg Ulcers

NCT ID: NCT01612806

Last Updated: 2024-04-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

31 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-06-30

Study Completion Date

2017-02-28

Brief Summary

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To evaluate the effectiveness of PriMatrix, PriMatrix Ag, and Standard of Care in the treatment of venous leg ulcers (VLUs).

Detailed Description

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Healing percentages

Conditions

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Venous Stasis Ulcer

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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PriMatrix

PriMatrix Dermal Repair Scaffold

Group Type EXPERIMENTAL

PriMatrix

Intervention Type DEVICE

fetal bovine dermal scaffold

moist wound therapy

Intervention Type PROCEDURE

standard of care moist wound therapy

PriMatrix Ag

PriMatrix Ag Antimicrobial Dermal Repair Scaffold

Group Type EXPERIMENTAL

PriMatrix Ag

Intervention Type DEVICE

fetal bovine dermal scaffold with Ag

moist wound therapy

Intervention Type PROCEDURE

standard of care moist wound therapy

Standard of Care

Standard of Care Moist Wound Therapy

Group Type ACTIVE_COMPARATOR

moist wound therapy

Intervention Type PROCEDURE

standard of care moist wound therapy

Interventions

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PriMatrix

fetal bovine dermal scaffold

Intervention Type DEVICE

PriMatrix Ag

fetal bovine dermal scaffold with Ag

Intervention Type DEVICE

moist wound therapy

standard of care moist wound therapy

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Men or women ≥ 18 years of age
* Ankle-brachial index (ABI) \> 0.80
* Study wound 2-64 cm2 surface area
* Wound does not exhibit a greater than 50% reduction in surface area during the screening period

Exclusion Criteria

* Suspected or confirmed signs/symptoms of wound infection
* Hypersensitivity to bovine collagen
* Body Mass Index (BMI) ≥ 45
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Integra LifeSciences Corporation

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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John Starinski, DPM

Role: STUDY_DIRECTOR

TEI

Locations

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Caribbean Clinical Trials

San Juan, PR, Puerto Rico

Site Status

Dr. Pila Metropolitan Hospital Wound Healing Center

Ponce, , Puerto Rico

Site Status

Doctors' Center Hospital of San Juan

San Juan, , Puerto Rico

Site Status

Wound and Ulcer Care Clinic of San Juan

San Juan, , Puerto Rico

Site Status

Wilma N. Vazquez Hospital

Vega Baja, , Puerto Rico

Site Status

Countries

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Puerto Rico

Other Identifiers

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TEI-006

Identifier Type: -

Identifier Source: org_study_id

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