NUPRO(r) Sensodyne Prophylaxis Paste With NovaMin(r)Sensitivity Relief Study

NCT ID: NCT01610167

Last Updated: 2013-10-14

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

View full results

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

151 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-09-30

Study Completion Date

2011-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The study is intended to verify through clinical measurement that the NUPRO Sensodyne Prophylaxis Paste with Novamin provides immediate sensitivity relief as well as extended relief up to 28 days.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

It is hypothesized that the prophy paste with NovaMin(r)will give patients immediate sensitivity relief, as well as sensitivity relief up to 4 weeks (28 days) after measurement.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Tooth Hypersensitivity

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Caregivers Investigators

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

NUPRO(r) Classic Prophy Paste

Group Type ACTIVE_COMPARATOR

NUPRO Classic Prophy Paste

Intervention Type DEVICE

Abrasive, flavored dental prophylaxis paste for cleaning and polishing teeth.

NUPRO Sensodyne Prophy Paste w/ Novamin(r) w/ fluoride.

Group Type EXPERIMENTAL

NUPRO Sensodyne Prophy Paste with Novamin with fluoride.

Intervention Type DEVICE

Abrasive, flavored dental prophylaxis paste for cleaning and polishing teeth.

NUPRO Sensodyne Prophy Paste w/ Novamin

Group Type EXPERIMENTAL

NUPRO Sensodyne Prophy Paste with Novamin without fluoride.

Intervention Type DEVICE

Abrasive, flavored dental prophylaxis paste for cleaning and polishing teeth.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

NUPRO Classic Prophy Paste

Abrasive, flavored dental prophylaxis paste for cleaning and polishing teeth.

Intervention Type DEVICE

NUPRO Sensodyne Prophy Paste with Novamin with fluoride.

Abrasive, flavored dental prophylaxis paste for cleaning and polishing teeth.

Intervention Type DEVICE

NUPRO Sensodyne Prophy Paste with Novamin without fluoride.

Abrasive, flavored dental prophylaxis paste for cleaning and polishing teeth.

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Availability to complete in the 28 day duration of the study.
* Two sensitive teeth which are not adjacent to each other and preferably in different quadrants and demonstrate cervical erosion, abrasion, and gingival recession.
* qualifying response to tactile stimuli as defined by a score of \</= 20 grams.
* Qualifying response to air blast stimuli as defined by a score of \>/= 1 on the Schiff Cold Air Sensitivity Scale.
* Good general health with no known allergies to products being tested.
* Use of a non-desensitizing dentifrice for 3 weeks prior to entry into the study.
* Able to follow study procedures and instructions.
* Must have a minimum of 10 natural evaluable teeth, excluding 3rd molars.

Exclusion Criteria

* Individuals who exhibit gross oral pathology
* Females who may be pregnant or lactating or intending to become pregnant
* Individuals who require anesthetic during scaling
* Dental pathology which may cause pain similar to tooth sensitivity
* Individuals with large amounts of calculus
* Subjects with active infectious diseases such as hepatitis, HIV or tuberculosis
* Any condition requiring antibiotic prophylaxis for dental treatment
* Excessive gingival inflammation
* Individuals who had their teeth cleaned within 30 days of the screening appointment
* Individuals who have had a desensitizing treatment or tooth bleaching within 90 days of screening appointment.
* Oral pathology, chronic disease, or history of allergy to test products
* Advanced periodontal disease or treatment for periodontal disease (including surgery) within the past twelve months.
* Sensitive teeth with mobility greater than one.
* Teeth with extensive/defective restorations (including prosthetic crowns), suspected pulpitis, caries, cracked enamel, or used as abutments for removable partial dentures.
* Regular use of sedatives, anti-inflammatory drugs, or analgesic
* Participation in a desensitizing dentifrice study or regular use of a desensitizing dentifrice within the past 4 weeks.
* Current participation in any other clinical study or receipt of an investigational drug within 30 days of the screening visit at the start of the study.
* Personnel; a) An employee of the sponsor; b) A member or relative of the study site staff directly involved with the study.
* Allergies to oral care products, personal care consumer products, or their ingredients.
* Any subject who, in the judgment of the investigator, should not participate in the study.
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Dentsply International

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Jeffery L. Milleman, DDS, MPA

Role: PRINCIPAL_INVESTIGATOR

Salus Research

Kimberly R. Milleman, ASDH, MS

Role: PRINCIPAL_INVESTIGATOR

Salus Research

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Salus Research

Fort Wayne, Indiana, United States

Site Status

Countries

Review the countries where the study has at least one active or historical site.

United States

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

CTP-001

Identifier Type: -

Identifier Source: org_study_id