Vascular Endothelial Growth Factor Levels in Ectopic Pregnancy

NCT ID: NCT01601964

Last Updated: 2015-08-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-05-31

Study Completion Date

2013-02-28

Brief Summary

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The aim of this study is to determine plasma Vascular Endothelial Growth Factor level and change in patient with ectopic pregnancy who needs to surgical treatment.

Patient with ectopic pregnancy diagnosed and treated with medically or surgically will be included in the study. This is an observational study.The plasma Vascular Endothelial Growth Factor level will be measured first day and two day after the diagnosis of ectopic pregnancy.

Detailed Description

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This study is a prospective, observational, single-center study. Ethical approval was obtained from the Institutional Review Board. This study will be completed with 30 patients with ectopic pregnancy. An intervenous cannula will be centrifuged for 15 minutes at 1000 g within 30 minutes of collection. Aliquots of plasma will be added to eppendorf tubes and stored at -20°C.

Plasma Vascular Endothelial Growth Factor levels will be measured using a Human VEGF-A Platinum ELISA kit (bioscience company, Catalog No: 00122, Santa Clara, California, USA). All assays will be performed according to the manufacturer's instructions. The test kit sensitivity is 2.5 pg/ml. Intracycle variability is %4-6, intercycle variability is %8-10.

Conditions

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Complication Following Ectopic Pregnancy

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Follow-up or medical treatment.

medical treatment

No interventions assigned to this group

Surgical treatment

Surgical treatment

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Patients who suspected ectopic pregnancy

Exclusion Criteria

* hemodynamically unstable patient
* healthy pregnancy (a healthy increase in ß HCG)
* missed abortion
* incomplete abortion
* The patient who need immediate surgical treatment
Minimum Eligible Age

18 Years

Maximum Eligible Age

46 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Bagcilar Training and Research Hospital

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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TANER A USTA, M.D.

Role: PRINCIPAL_INVESTIGATOR

Bagcilar Training and Research Hospital, Istanbul, Turkey.

Locations

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Bagcilar Training and Research Hospital

Istanbul, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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BEH GynObs-1

Identifier Type: -

Identifier Source: org_study_id

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