Effectiveness and Safety Confirmation Between FASTSEAL® Bioabsorbable VCD and Perclose® ProGlide SMC System

NCT ID: NCT01597570

Last Updated: 2017-07-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

PHASE3

Total Enrollment

52 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-05-31

Study Completion Date

2012-12-10

Brief Summary

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It is purposed to verify a superiority of the Fastseal® Bioabsorbable Vascular Access Closure System through effectiveness and safety confirmation of hemostasis (TTH; Time to hemstasis) and ambulation (TTA; Time to ambulation) at the puncture site of common femoral artery (CFA) after the procedures of Fastseal® Biosorbable Vascular Access Closure System or Perclose® ProGlide Suture-Mediated Closure System during 1 month observation.

Detailed Description

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Prospective, Single blind, randomized

Comparative study using the Fastseal® Bioabsorbable Vascular Access Closure System as an investigational device and the Perclose® ProGlide Suture-Mediated Closure System as a comparator.

After going through the confirmation of inclusion/exclusion criteria with signed subjects, they will have a procedure either of the two devices. The subjects should follow designated physician's instructions accurately during the clinical trial period.There are about 6 times evaluations Including screening.

Conditions

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The Patients Who Needed Hemostasis at the Puncture Site of Common Femoral Artety(CFA) Caused by Femoral Angiogram or Intervention After the Catheter Removal

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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FASTSEAL® Bioabsorbable VCD

Fastseal® Bioabsorbable Vascular Access Closure System

Group Type EXPERIMENTAL

Vascular Closure Device

Intervention Type DEVICE

To reduce the TTH(Time to hemostasis) and TTA(Time to ambulation)of common femoral artery(CFA) puncture site

Perclose® ProGlide SMC System

Perclose® ProGlide Suture-Mediated Closure System

Group Type ACTIVE_COMPARATOR

Vascular Closure Device

Intervention Type DEVICE

To reduce the TTH(Time to hemostasis) and TTA(Time to ambulation)of common femoral artery(CFA) puncture site

Interventions

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Vascular Closure Device

To reduce the TTH(Time to hemostasis) and TTA(Time to ambulation)of common femoral artery(CFA) puncture site

Intervention Type DEVICE

Other Intervention Names

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FASTSEAL® Bioabsorbable Vascular Access Closure System / Perclose® ProGlide Suture-Mediated Closure System

Eligibility Criteria

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Inclusion Criteria

* Between 20 years old and 85 years old, randomized
* Patient who submitted a written informed consent for the this trial
* The subjects should be scheduled to have an angiography or intervention through the common femoral artery (CFA).
* The subjects must be used a 6Fr sheath of the Terumo's RadiFocus Introducer II.

Exclusion Criteria

* In case of the subject has a functure site in both legs.
* The patient who had the closing device insertion or manual compression at the targeted femoral artery within 30 days
* Patients with severe bleeding disorders (Severe bleeding history, blood coagulation disorder, thrombocytopenia (under 100,000 of platelet count), hemophilia, anemia (Hgb\<10g/dL, Hct\<30%), Thrombasthenia, any related bleeding disorder
* Hypertension patient BP ≥180/110mmHg
* In case of thrombolysis(ex: streptokinase, urokinase, t-PA) within 24hr
* If there is any hematoma, arteriovenous fistula(AVF), false aneurysm existed at the access site of femoral artery
* Severe obesity BMI \> 40kg/m2
* In case of prior stent placement or artificial vessel insertion in the common femoral artery(CFA)
* Under 5mm of Common femoral artery (CFA) diameter
Minimum Eligible Age

20 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Taewoong Medical Co., Ltd.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Dongik Kim, Professor Dr.

Role: PRINCIPAL_INVESTIGATOR

Severance Hospital / Radiology

Locations

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Samsung Medical Center

Seoul, Irwon-Dong, Gangnam-Gu, South Korea

Site Status

Severance Hospital

Seoul, Seodaemun Gu, South Korea

Site Status

Countries

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South Korea

Other Identifiers

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FASTSEAL® VCD

Identifier Type: -

Identifier Source: org_study_id

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