FR01 and FR20 IUS (Intrauterine System) Wearing Study

NCT ID: NCT01595022

Last Updated: 2015-04-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Total Enrollment

90 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-01-31

Study Completion Date

2010-09-30

Brief Summary

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The aim of the study is to evaluate two different placebo intrauterine systems, placebo FR01 and FR20 with different types of inserters, for wearing comfort, insertion/removal ease and pain compared to a placebo T-frame intrauterine system.

Detailed Description

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Conditions

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Contraception

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Participants

Study Groups

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Flexi ring FR01

Group Type PLACEBO_COMPARATOR

Placebo: Flexi ring FR01

Intervention Type DRUG

Intrauterine device, inserted once for 3 months

Flexi ring FR20

Group Type PLACEBO_COMPARATOR

Placebo: Flexi ring FR20

Intervention Type DRUG

Intrauterine device, inserted once for 3 months

Ultra low dose LCS

Group Type PLACEBO_COMPARATOR

Placebo: Ultra low dose levonorgestrel contraceptive system (LCS)

Intervention Type DRUG

Intrauterine device, inserted once for 3 months

Interventions

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Placebo: Flexi ring FR01

Intrauterine device, inserted once for 3 months

Intervention Type DRUG

Placebo: Flexi ring FR20

Intrauterine device, inserted once for 3 months

Intervention Type DRUG

Placebo: Ultra low dose levonorgestrel contraceptive system (LCS)

Intrauterine device, inserted once for 3 months

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Healthy Female subject
* Age 18-40 years (inclusive)
* History of regular cyclic menstrual periods at baseline (cycle length 21 to 35 days)
* Women using any COC (combined oral contraceptive) for contraception with a monthly regimen before the study entry.
* Confirmed uterine sound depth of 6 to 10 cm

Exclusion Criteria

* Pregnancy or lactation
* Sterilized
* Nulliparous
* Congenital or acquired uterine anomaly
* Vaginal or cesarean delivery within 8 weeks prior to insertion
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Bayer

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Bayer Study Director

Role: STUDY_DIRECTOR

Bayer

Locations

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Helsinki, , Finland

Site Status

Kuopio, , Finland

Site Status

Tampere, , Finland

Site Status

Turku, , Finland

Site Status

Den Helder, , Netherlands

Site Status

Heerlen, , Netherlands

Site Status

Zwijndrecht, , Netherlands

Site Status

Örebro, , Sweden

Site Status

Stockholm, , Sweden

Site Status

Uppsala, , Sweden

Site Status

Countries

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Finland Netherlands Sweden

Other Identifiers

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13830

Identifier Type: -

Identifier Source: org_study_id

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