The Parkinson's Genetic Research Study

NCT ID: NCT01558479

Last Updated: 2024-05-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

5000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-09-30

Study Completion Date

2026-10-31

Brief Summary

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The Parkinson's Genetic Research Study (PaGeR), headed by Dr. Cyrus Zabetian, is searching for genes that increase the risk of developing Parkinson's disease (PD) and related disorders. The study is a joint effort by neurologists and researchers across the United States and is sponsored by the National Institutes of Health. The coordinating center for PaGeR is located at the University of Washington and the VA Puget Sound Health Care System in Seattle.

Detailed Description

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PaGeR is focusing on families in which two or more people have been diagnosed with PD. Past research suggests that such "multiplex" families might hold the key to the discovery of new PD genes.

To take part in PaGeR, participants will be asked to complete a questionnaire and to undergo an interview, a neurological exam, a short memory test, and a blood draw. Enrollment in the study usually takes between one and two hours. There is no cost to participate, and all study information is kept strictly confidential.

There are a number of designated sites across the country where families can enroll. However, for family members who are unable to travel to one of these sites, other arrangements can be made.

Conditions

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Parkinson's Disease

Study Design

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Observational Model Type

FAMILY_BASED

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Case

Has a diagnosis of Parkinson's disease

No interventions assigned to this group

Control

No diagnosis of Parkinson's disease

No interventions assigned to this group

Family Member

Has a family history of Parkinson's disease. Can be affected or unaffected with Parkinson's disease

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Over 18 years of age
* Member of a family in which there are two or more living individuals who have been diagnosed with Parkinson's disease

Exclusion Criteria

* Under 18 years of age
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Washington

OTHER

Sponsor Role lead

Responsible Party

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Cyrus Zabetian

Professor of Neurology

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Cyrus Zabetian, MD, MS

Role: PRINCIPAL_INVESTIGATOR

University of Washington, VA Puget Sound Health Care System

Locations

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Emory University/ Wesley Woods Health Center

Atlanta, Georgia, United States

Site Status RECRUITING

University of Cincinnati

Cincinnati, Ohio, United States

Site Status RECRUITING

Portland VA Medical Center

Portland, Oregon, United States

Site Status RECRUITING

VA Puget Sound Health Care System

Seattle, Washington, United States

Site Status RECRUITING

University of Washington

Seattle, Washington, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Jennifer Pate

Role: CONTACT

1-855-646-4221

Khryss Capawa

Role: CONTACT

(206) 277-3956

Facility Contacts

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Barbara Sommerfield, MSN, RN

Role: primary

404-728-6944

Jatue Krier

Role: primary

513-558-0169

Susan O'Connor

Role: primary

503-220-8262 ext. 53262

Jennifer Pate

Role: primary

855-646-4221

Jennifer Pate

Role: primary

855-646-4221

Related Links

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Other Identifiers

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36777

Identifier Type: -

Identifier Source: org_study_id

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