A Clinical Study of Lyophilized Plasma in Patients on Warfarin

NCT ID: NCT01541098

Last Updated: 2015-03-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Clinical Phase

PHASE2

Study Classification

INTERVENTIONAL

Study Start Date

2015-01-31

Study Completion Date

2016-01-31

Brief Summary

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This is a multi center, phase 2 randomized controlled study to determine the effect of lyophilized plasma in patients on warfarin therapy.

Detailed Description

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Conditions

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Anticoagulant Therapy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Licensed Plasma

Group Type ACTIVE_COMPARATOR

Licensed Plasma

Intervention Type BIOLOGICAL

Plasma that has been authorized for transfusion.

Lyophilized Plasma

Group Type EXPERIMENTAL

Lyophilized Plasma

Intervention Type BIOLOGICAL

Licensed plasma that has been lyophilized.

Interventions

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Lyophilized Plasma

Licensed plasma that has been lyophilized.

Intervention Type BIOLOGICAL

Licensed Plasma

Plasma that has been authorized for transfusion.

Intervention Type BIOLOGICAL

Eligibility Criteria

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Inclusion Criteria

1. Patients receiving oral anticoagulation with warfarin derived agents.
2. Patients who have need for urgent surgery, an invasive procedure or identification of a patient with active bleeding where oral or parenteral vitamin K therapy is deemed too slow in its action for reversal of warfarin anticoagulant effects.
3. Patients with an elevated international normalized ratio.

Exclusion Criteria

1. Patients who are clinically unstable.
2. Patients who have congenital or acquired coagulopathies (other than warfarin therapy).
3. Patients who have received medications that could interfere with the results of laboratory testing.
4. Pregnant or nursing women.
5. Patients participating in another clinical treatment study currently or during the past 1 month prior to study inclusion.
6. Patients previously enrolled in this study.
7. Active illicit drug use.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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HemCon Medical Technologies, Inc

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Other Identifiers

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2011-I-LyP-1

Identifier Type: -

Identifier Source: org_study_id

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