Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
328 participants
INTERVENTIONAL
2011-07-31
2018-06-30
Brief Summary
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Detailed Description
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Three groups will be recruited: Maltreated Depressive Symptoms (MDS), Nonmaltreated Depressive Symptoms (NDS), and a Nonmaltreated Nonsymptomatic Comparison (NNC), comparable in SES, race/ethnicity, and household composition. The MDS and NDS groups will be randomized into IPT-A or Enhanced Care (EC). Adolescent girls in these groups will receive 13 sessions of therapy. Girls in the NNC group will only complete research visits.
Research assessments will be conducted at T1 (baseline/prior to intervention), T2 (6-weeks mid-intervention), T3 (end of intervention), T4 (1-year post) and T5 (18 months post). Girls and their mothers will participate in these research sessions. A multi-level-of-analysis approach, integrating genotyping, hormone assays, cognitive testing, adolescent- and maternal-report, mother-teen observation, and DHS and school records will be utilized to assess the effectiveness of the interventions.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
NONE
Study Groups
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Interpersonal Psychotherapy
Adolescents will receive Interpersonal Psychotherapy for the treatment and prevention of depression.
Interpersonal Psychotherapy for Adolescents
Adolescents will receive IPT-A a manualized intervention for depression and prevention of depression that emphasizes current interpersonal relationships, focusing on their immediate social context.
Enhanced Care
Adolescents will receive the Enhanced care model or care that they would typically receive in community setting to treat and prevent depression.
Enhanced Care
Adolescents will receive enhanced care which is consistent with care typically provided in community settings to treat and prevent depression.
Interventions
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Interpersonal Psychotherapy for Adolescents
Adolescents will receive IPT-A a manualized intervention for depression and prevention of depression that emphasizes current interpersonal relationships, focusing on their immediate social context.
Enhanced Care
Adolescents will receive enhanced care which is consistent with care typically provided in community settings to treat and prevent depression.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* ages 13-15 years old
* low SES status
* live in Rochester or surrounding counties
* girls in the maltreated depressive symptom group will have CPS-documented child maltreatment
* girls in the nonmaltreated depressive symptom group will not have CPS- documented child maltreatment
* girls in the nonmaltreated nonsymptomatic comparison group will have no current or past mental illness and no documented child maltreatment
Exclusion Criteria
* already receiving mental health treatment
* actively suicidal
* diagnosed with a severe mental disorder
* abusing drugs or alcohol
* evidence of compromised cognitive ability
* evidence of a pervasive developmental disorder
* evidence of a major physical or neurological disorder
* non-English speaking
13 Years
15 Years
FEMALE
Yes
Sponsors
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National Institute of Mental Health (NIMH)
NIH
University of Rochester
OTHER
Responsible Party
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Sheree Toth
Director Mt. Hope Family Center
Principal Investigators
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Sheree Toth, PhD
Role: PRINCIPAL_INVESTIGATOR
University of Rochester
Dante Cicchetti, Ph.D.
Role: PRINCIPAL_INVESTIGATOR
University of Minnesota
Locations
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Mt. Hope Family Center
Rochester, New York, United States
Countries
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Other Identifiers
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035457
Identifier Type: -
Identifier Source: org_study_id
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