Remote Monitoring of Chronic Heart Failure in Veneto Region

NCT ID: NCT01513993

Last Updated: 2015-10-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

315 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-10-31

Study Completion Date

2014-05-31

Brief Summary

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The purpose of this study is to evaluate whether telemonitoring of patients with chronic heart failure produces a reduction in the combined end point of all cause mortality and number of hospitalisations, and whether it improves health related quality of life. In addition, the trials evaluate the economic and organisational impact of the telemonitoring service and examine its acceptability by patients and health professionals.

Detailed Description

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The study is designed to evaluate the impact of telemonitoring on the management of CHF compared with outpatient usual care. From a clinical point of view, the trial will allow to investigate how telemonitoring contributes to reduct the combined end point of all cause mortality and re-hospitalizations, as well as the other kinds of access to hospital facilities (bed-days, specialistic and ER visits). The trial will examine whether the CHF patients improve their health-related quality of life and reduct the anxiety about health conditions, thanks to the telemonitoring. A cost-effectiveness and cost-utility analysis will be carried out in order to determine if and how telemonitoring helps to limit the healthcare expenditure. The evaluation will deal also with organizational changes and task shift due to telemonitoring introduction and patients and professional perception towards the service.

Conditions

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Congestive Heart Failure

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Control group

Treatment as usual

Group Type NO_INTERVENTION

No interventions assigned to this group

Telemonitoring for patients with Congestive Heart Failure

Group Type EXPERIMENTAL

Telemonitoring for patients with Congestive Heart Failure

Intervention Type PROCEDURE

Patients are equipped with a telemonitoring kit composed by a portable wrist-clinic device and digital weight scale for clinical parameters measuring and a gateway device for data transmission.

The patient can monitor a complete set of clinical parameters, such as pulse-oxymetry, heart rate, blood pressure, ECG and body weight, with a frequency set by the clinician in the personalised treatment plan. Data are transmitted to a regional eHealth centre where a group of operators keeps these information under control and alerts the reference clinician in case of worsening of symptoms.

Interventions

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Telemonitoring for patients with Congestive Heart Failure

Patients are equipped with a telemonitoring kit composed by a portable wrist-clinic device and digital weight scale for clinical parameters measuring and a gateway device for data transmission.

The patient can monitor a complete set of clinical parameters, such as pulse-oxymetry, heart rate, blood pressure, ECG and body weight, with a frequency set by the clinician in the personalised treatment plan. Data are transmitted to a regional eHealth centre where a group of operators keeps these information under control and alerts the reference clinician in case of worsening of symptoms.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Age ≥ 65 years.
* Discharge from hospital after acute heart failure in the previous 3 months and EF \< 40% or EF \> 40% plus BNP \> 400 (or plus NT-proBNP\>1500) during hospitalization

Exclusion Criteria

* Comorbidities prevalent on CHF with life expectation \< 12 months.
* Impossibility or inability to use the equipment and help at home not available.
* Myocardial infarction or percutaneous coronary intervention in the last 3 months or scheduled.
* Coronary artery bypass, valve substitution or correction in the last 6 months.
* Being on waiting list for heart transplantation.
* Being enrolled in other trial
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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European Commission

OTHER

Sponsor Role collaborator

Azienda Unità Locale Socio Sanitaria n.9 Treviso

OTHER

Sponsor Role collaborator

Azienda ULSS 7 Conegliano

OTHER

Sponsor Role collaborator

Azienda ULSS 16 Padova

OTHER

Sponsor Role collaborator

Azienda ULSS di Verona e Provincia

OTHER

Sponsor Role collaborator

Azienda ULSS 12 Veneziana

OTHER

Sponsor Role collaborator

Azienda Unità Socio Sanitaria di Dolo Mirano

OTHER

Sponsor Role collaborator

Azienda Ospedaliera di Padova

OTHER

Sponsor Role collaborator

Azienda Ospedaliera Universitaria Integrata Verona

OTHER

Sponsor Role collaborator

Regione Veneto

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Zoran Olivari, DM

Role: PRINCIPAL_INVESTIGATOR

Azienda Unità Locale Socio Sanitaria n.9 Treviso

Locations

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Azienda Ospedaliera di Padova - Cardiology Department

Padua, Padova, Italy

Site Status

Ospedale Immacolata Concezione - Cardiology Department

Piove di Sacco, Padova, Italy

Site Status

Presidio ospedaliero di Conegliano - Department of Cardiology

Conegliano, Treviso, Italy

Site Status

Ospedale Ca'Foncello - Pulmonology Department

Treviso, Treviso, Italy

Site Status

Ospedale di Mirano - Cardiology Department

Mirano, Venezia, Italy

Site Status

Ospedale SS Giovanni e Paolo - Cardiology Department

Venezia, Venezia, Italy

Site Status

Ospedale San Fracastoro - Cardiology Department

San Bonifacio, Verona, Italy

Site Status

Azienda Ospedaliera Universitaria Integrata di Verona - Geriatric Medicine Department

Verona, Verona, Italy

Site Status

Countries

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Italy

References

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Scherr D, Kastner P, Kollmann A, Hallas A, Auer J, Krappinger H, Schuchlenz H, Stark G, Grander W, Jakl G, Schreier G, Fruhwald FM; MOBITEL Investigators. Effect of home-based telemonitoring using mobile phone technology on the outcome of heart failure patients after an episode of acute decompensation: randomized controlled trial. J Med Internet Res. 2009 Aug 17;11(3):e34. doi: 10.2196/jmir.1252.

Reference Type BACKGROUND
PMID: 19687005 (View on PubMed)

Clark RA, Inglis SC, McAlister FA, Cleland JG, Stewart S. Telemonitoring or structured telephone support programmes for patients with chronic heart failure: systematic review and meta-analysis. BMJ. 2007 May 5;334(7600):942. doi: 10.1136/bmj.39156.536968.55. Epub 2007 Apr 10.

Reference Type BACKGROUND
PMID: 17426062 (View on PubMed)

Inglis SC, Clark RA, McAlister FA, Stewart S, Cleland JG. Which components of heart failure programmes are effective? A systematic review and meta-analysis of the outcomes of structured telephone support or telemonitoring as the primary component of chronic heart failure management in 8323 patients: Abridged Cochrane Review. Eur J Heart Fail. 2011 Sep;13(9):1028-40. doi: 10.1093/eurjhf/hfr039. Epub 2011 Jul 6.

Reference Type BACKGROUND
PMID: 21733889 (View on PubMed)

Chaudhry SI, Mattera JA, Curtis JP, Spertus JA, Herrin J, Lin Z, Phillips CO, Hodshon BV, Cooper LS, Krumholz HM. Telemonitoring in patients with heart failure. N Engl J Med. 2010 Dec 9;363(24):2301-9. doi: 10.1056/NEJMoa1010029. Epub 2010 Nov 16.

Reference Type BACKGROUND
PMID: 21080835 (View on PubMed)

Klersy C, De Silvestri A, Gabutti G, Regoli F, Auricchio A. A meta-analysis of remote monitoring of heart failure patients. J Am Coll Cardiol. 2009 Oct 27;54(18):1683-94. doi: 10.1016/j.jacc.2009.08.017.

Reference Type BACKGROUND
PMID: 19850208 (View on PubMed)

Inglis SC, Clark RA, McAlister FA, Ball J, Lewinter C, Cullington D, Stewart S, Cleland JG. Structured telephone support or telemonitoring programmes for patients with chronic heart failure. Cochrane Database Syst Rev. 2010 Aug 4;(8):CD007228. doi: 10.1002/14651858.CD007228.pub2.

Reference Type BACKGROUND
PMID: 20687083 (View on PubMed)

Related Links

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http://www.renewinghealth.eu

The Renewing Health project is partially funded under the ICT Policy Support Programme (ICT PSP) as part of the Competitiveness and Innovation Framework Programme by the European Community

Other Identifiers

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G. A. 250487-Veneto WP8Cl7

Identifier Type: -

Identifier Source: org_study_id

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