Prophylactic Central Neck Dissection for Papillary Thyroid Cancer
NCT ID: NCT01510002
Last Updated: 2012-01-13
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
640 participants
INTERVENTIONAL
1993-01-31
2011-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
CROSSOVER
TREATMENT
NONE
Study Groups
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TT
Extracapsular total thyroidectomy
Total thyroidectomy
Extracapsular total thyroidectomy
TT+CND
Extracapsular total thyroidectomy puls prophylactic central neck dissection
Total thyroidectomy + prophylactic central neck dissection
Extracapsular total thyroidectomy plus prophylactic central neck dissection
Interventions
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Total thyroidectomy
Extracapsular total thyroidectomy
Total thyroidectomy + prophylactic central neck dissection
Extracapsular total thyroidectomy plus prophylactic central neck dissection
Eligibility Criteria
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Inclusion Criteria
* in a patient with negative cervical lymph nodes on pre-, or intraoperative evaluation
Exclusion Criteria
* one-stage lymph nodes dissection based on therapeutic intent,
* previous thyroid surgery,
* incomplete follow-up information,
* incomplete histopathology report,
* ASA grade higher than 3 (American Society of Anesthesiology)
18 Years
ALL
No
Sponsors
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Jagiellonian University
OTHER
Responsible Party
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Marcin Barczynski
Principal Investigator
Principal Investigators
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Marcin Barczynski, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
Jagiellonian University
Locations
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Jagiellonian Univerity, Medical College, 3rd Department of General Surgery
Krakow, Malopolska, Poland
Countries
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References
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Forest VI, Clark JR, Ebrahimi A, Cho EA, Sneddon L, Gao K, O'brien CJ. Central compartment dissection in thyroid papillary carcinoma. Ann Surg. 2011 Jan;253(1):123-30. doi: 10.1097/SLA.0b013e3181fc9644.
Mulla M, Schulte KM. Central cervical lymph node metastases in papillary thyroid cancer: a systematic review of imaging-guided and prophylactic removal of the central compartment. Clin Endocrinol (Oxf). 2012 Jan;76(1):131-6. doi: 10.1111/j.1365-2265.2011.04162.x.
Popadich A, Levin O, Lee JC, Smooke-Praw S, Ro K, Fazel M, Arora A, Tolley NS, Palazzo F, Learoyd DL, Sidhu S, Delbridge L, Sywak M, Yeh MW. A multicenter cohort study of total thyroidectomy and routine central lymph node dissection for cN0 papillary thyroid cancer. Surgery. 2011 Dec;150(6):1048-57. doi: 10.1016/j.surg.2011.09.003.
Alvarado R, Sywak MS, Delbridge L, Sidhu SB. Central lymph node dissection as a secondary procedure for papillary thyroid cancer: Is there added morbidity? Surgery. 2009 May;145(5):514-8. doi: 10.1016/j.surg.2009.01.013. Epub 2009 Mar 27.
Grodski S, Cornford L, Sywak M, Sidhu S, Delbridge L. Routine level VI lymph node dissection for papillary thyroid cancer: surgical technique. ANZ J Surg. 2007 Apr;77(4):203-8. doi: 10.1111/j.1445-2197.2007.04019.x.
Moo TA, Umunna B, Kato M, Butriago D, Kundel A, Lee JA, Zarnegar R, Fahey TJ 3rd. Ipsilateral versus bilateral central neck lymph node dissection in papillary thyroid carcinoma. Ann Surg. 2009 Sep;250(3):403-8. doi: 10.1097/SLA.0b013e3181b3adab.
Barczynski M, Konturek A, Stopa M, Cichon S, Richter P, Nowak W. Total thyroidectomy for benign thyroid disease: is it really worthwhile? Ann Surg. 2011 Nov;254(5):724-29; discussion 729-30. doi: 10.1097/SLA.0b013e3182360118.
Barczynski M, Konturek A, Stopa M, Nowak W. Prophylactic central neck dissection for papillary thyroid cancer. Br J Surg. 2013 Feb;100(3):410-8. doi: 10.1002/bjs.8985. Epub 2012 Nov 27.
Other Identifiers
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BBN/501/ZKL/1447
Identifier Type: -
Identifier Source: org_study_id
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