Prophylactic Selective Lateral Neck Dissection in Patients With Papillary Thyroid Carcinoma

NCT ID: NCT01103557

Last Updated: 2010-04-14

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 62 participants
• Study Classification: INTERVENTIONAL

Brief Summary

The purpose of this study is to prospectively analyze the incidence of occult lateral neck metastasis (LNM) and to elucidate the factors that predict LNM in papillary thyroid carcinoma (PTC) with central neck metastasis (CNM) by performing prophylactic selective lateral neck dissection (SND).

Detailed Description

The lymphatic drainage pattern of the thyroid is uniform and consistent, and therefore, metastatic patterns are relatively predictable. Initial nodal metastasis in PTC usually occurs in the paratracheal and pretracheal nodes in level VI of the central compartment of the ipsilateral neck and spreads to the lateral cervical lymph nodes. Macroscopic skip metastases to the lateral compartment of the neck in the absence of central disease are uncommon.

Conditions

Thyroid Neoplasm; Lymphatic Metastasis

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: DIAGNOSTIC
• Blinding Strategy: NONE

Interventions

prophylactic selective lateral neck dissection

Level II, III, IV lymph node dissection

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

• Papillary thyroid carcinoma with central neck metastasis
• No evidence of lateral neck metastasis as determined by high-resolution neck ultrasonography and computed tomography

Exclusion Criteria

• History of previous thyroid operation
• Isthmic thyroid lesion

• Minimum Eligible Age: 20 Years
• Maximum Eligible Age: 76 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Pusan National University Hospital

OTHER

Sponsor Role: lead

Responsible Party

Pusan National University Hospital

Other Identifiers

PTC_CND_LND

Identifier Type: -

Identifier Source: org_study_id