Routine Follow-up Versus Self-assessment in Medical Abortion

NCT ID: NCT01487213

Last Updated: 2013-08-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

929 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-09-30

Study Completion Date

2013-07-31

Brief Summary

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The main objective of the study is to optimize the routines for follow-up after medical abortion in order to give women more autonomy by reducing the number of consultations involved and to reduce the frequency of postabortal curettage.

This will be achieved by providing means for women for postabortal self-assessment with the use of a quantitative urinary hCG test.

Detailed Description

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Conditions

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Medical Abortion

Keywords

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Medical abortion Termination of pregnancy Mifepristone Misoprostol Urine hCG Follow Up Termination of unwanted pregnancy. Self assessment (follow up) after medical abortion

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

NONE

Study Groups

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Controls

Routine follow-up at the clinic 2-3 weeks after the treatment

Group Type NO_INTERVENTION

No interventions assigned to this group

Home self test

Intervention

Group Type OTHER

Home self assessment of complete medical abortion

Intervention Type OTHER

Self assessment of complete abortion using a home semiquantitative U-hCG test. Follow-up out patient review two-three weeks later by qualified practitioner to evaluate success of procedure using the clinic's standard routine. The patient charts will be reviewed after three months in order to control for possible extra visits related to abortion-related complications.

Interventions

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Home self assessment of complete medical abortion

Self assessment of complete abortion using a home semiquantitative U-hCG test. Follow-up out patient review two-three weeks later by qualified practitioner to evaluate success of procedure using the clinic's standard routine. The patient charts will be reviewed after three months in order to control for possible extra visits related to abortion-related complications.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* women requesting termination of pregnancy by means of mifepristone followed by home administration of misoprostol at \< /=63 days of gestation, with no contraindication to medical abortion and self administration of misoprostol at home, and who have given their informed consent will be eligible for study recruitment.

Exclusion Criteria

* women who do not wish to participate
* women who do not want home administration of misoprostol
* women who are unable to communicate in Swedish, Norwegian, English, Finnish or German and women with symptoms and signs of ectopic pregnancy
* minors (i.e. women \< 18 years of age) will not be enrolled for the study.
* women seeking termination of pregnancy with no sign of a visible intrauterine pregnancy (i.e. visible intrauterine yolk sac).
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Ullevaal University Hospital

OTHER

Sponsor Role collaborator

University of Helsinki

OTHER

Sponsor Role collaborator

Gynmed Clinic Vienna

OTHER

Sponsor Role collaborator

Karolinska Institutet

OTHER

Sponsor Role lead

Responsible Party

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Kristina Gemzell Danielsson

professor, MD, PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Kristina Gemzell-Danielsson, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Karolinska Institutet

Locations

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GynMed Clinic

Vienna, , Austria

Site Status

Dept. Obstetrics and Gynaecology,Helsinki University Central Hospital

Helsinki, , Finland

Site Status

Faculty of Medicine, University of Oslo and Dept. of Gynaecology,

Oslo, , Norway

Site Status

Dept of Obstetrics and Gynecology, Karolinska University Hospital

Stockholm, , Sweden

Site Status

Countries

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Austria Finland Norway Sweden

References

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Oppegaard KS, Qvigstad E, Fiala C, Heikinheimo O, Benson L, Gemzell-Danielsson K. Clinical follow-up compared with self-assessment of outcome after medical abortion: a multicentre, non-inferiority, randomised, controlled trial. Lancet. 2015 Feb 21;385(9969):698-704. doi: 10.1016/S0140-6736(14)61054-0. Epub 2014 Oct 30.

Reference Type DERIVED
PMID: 25468164 (View on PubMed)

Other Identifiers

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WNI1000

Identifier Type: -

Identifier Source: org_study_id