Pain After Intravitreal Therapy

NCT ID: NCT01477996

Last Updated: 2016-01-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

200 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-08-31

Study Completion Date

2011-12-31

Brief Summary

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This randomized clinical trial is comparing two different needles (27 gauge versus 30 gauge) for intravitreal therapy (IVT). Standardized questionnaires and pain scales should allow for standard recommendation regarding the optimal needle size for IVT.

Detailed Description

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Purpose: To evaluate the influence of the type of the needle on pain scores after intravitreal therapy (IVT).

Design: Randomized clinical trial Methods: A total of 200 patients, treated with an IVT for exudative age-related macular degeneration (AMD) or a vascular retinal disease, will be included and randomly assigned to be treated with either a 27-gauge needle (group 1) or a 30-gauge needle (group 2). After IVt the patient has to fill out a standardized questionnaire including pain scores on the visual analog scale after the surgical procedure.

Regression analysis of the scaled questionnaires should allow for a standard recommendation regarding the optimal needle size for minimal subjective pain during IVT.

Conditions

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Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Group 1

27-gauge needle

Group Type ACTIVE_COMPARATOR

27-gauge

Intervention Type PROCEDURE

27-gauge needle for IVT

Group 2

30-gauge needle

Group Type ACTIVE_COMPARATOR

30-gauge

Intervention Type PROCEDURE

30-gauge needle for IVT

Interventions

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27-gauge

27-gauge needle for IVT

Intervention Type PROCEDURE

30-gauge

30-gauge needle for IVT

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* vitrearetinal disease including age-related macular degeneration,
* clinical significant macular edema due to diabetic retinopathy or other vascular disorders
* treatment with intravitreal therapy

Exclusion Criteria

* missing informed consent
* age under 50 years
Minimum Eligible Age

51 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery

OTHER

Sponsor Role lead

Responsible Party

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Dr. Christiane I. Falkner-Radler

Principial investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Christiane I Falkner-Radler, MD

Role: PRINCIPAL_INVESTIGATOR

The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery

Susanne Binder, MD

Role: STUDY_CHAIR

The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery

Locations

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The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery, Department of Ophthalmology; Rudolf Foundation Clinic, Juchgasse 25

Vienna, , Austria

Site Status

Countries

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Austria

Other Identifiers

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FR-7-CI-2011

Identifier Type: -

Identifier Source: org_study_id

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