Efficacy and Safety of SPARC0921 in Subjects With Spasticity

NCT ID: NCT01457352

Last Updated: 2019-06-18

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

392 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-11-14

Study Completion Date

2017-08-25

Brief Summary

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The purpose of this study is to assess whether SPARC0921 demonstrate efficacy and safety in the treatment of spasticity.

Detailed Description

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Conditions

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Spasticity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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SPARC0921

Group Type EXPERIMENTAL

SPARC0921

Intervention Type DRUG

Placebo0921

Group Type PLACEBO_COMPARATOR

Placebo0921

Intervention Type DRUG

Interventions

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SPARC0921

Intervention Type DRUG

Placebo0921

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Men and women age 18 years and older
* Able and willing to comply with the protocol, including availability for a scheduled clinic visits
* Willingness and giving of written informed consent

Exclusion Criteria

* In relapse or history of unstable course over the prior 30 days prior to the Screening Visit
* Concomitant neurologic conditions causing spasticity
* Has received an investigational drug or device within 30 days that would interfere with the study goals prior to the Screening Visit
* Unable to comply with study procedures in the opinion of the investigator
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sun Pharma Advanced Research Company Limited

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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SPARC site 6

Gilbert, Arizona, United States

Site Status

SPARC Site 40

Phoenix, Arizona, United States

Site Status

SPARC Site 36

Costa Mesa, California, United States

Site Status

SPARC Site 20

Newport Beach, California, United States

Site Status

SPARC Site 38

Basalt, Colorado, United States

Site Status

SPARC Site 21

Denver, Colorado, United States

Site Status

SPARC Site 9

Derby, Connecticut, United States

Site Status

SPARC Site 57

Hartford, Connecticut, United States

Site Status

SPARC Site 10

New London, Connecticut, United States

Site Status

SPARC Site 60

Washington D.C., District of Columbia, United States

Site Status

SPARC Site 15

Bradenton, Florida, United States

Site Status

SPARC Site 54

Jacksonville, Florida, United States

Site Status

SPARC Site 41

Maitland, Florida, United States

Site Status

SPARC Site 70

Miami, Florida, United States

Site Status

SPARC Site 8

Ormond Beach, Florida, United States

Site Status

SPARC Site 17

Port Charlotte, Florida, United States

Site Status

SPARC Site 19

Sarasota, Florida, United States

Site Status

SPARC Site 31

Sunrise, Florida, United States

Site Status

SPARC Site 39

Tampa, Florida, United States

Site Status

SPARC Site 65

Tampa, Florida, United States

Site Status

SPARC Site 51

Lenexa, Kansas, United States

Site Status

SPARC Site 30

Overland Park, Kansas, United States

Site Status

SPARC Site 50

Louisville, Kentucky, United States

Site Status

SPARC Site 42

Alexandria, Louisiana, United States

Site Status

SPARC Site 27

Baton Rouge, Louisiana, United States

Site Status

SPARC Site 73

New Orleans, Louisiana, United States

Site Status

SPARC Site 35

Foxborough, Massachusetts, United States

Site Status

SPARC Site 23

Springfield, Massachusetts, United States

Site Status

SPARC Site 32

Clinton Township, Michigan, United States

Site Status

SPARC Site 64

Detroit, Michigan, United States

Site Status

SPARC Site 25

Golden Valley, Minnesota, United States

Site Status

SPARC Site 5

Henderson, Nevada, United States

Site Status

SPARC site 34

Flemington, New Jersey, United States

Site Status

SPARC Site 55

Stratford, New Jersey, United States

Site Status

SPARC Site 22

Albuquerque, New Mexico, United States

Site Status

SPARC Site 49

Rochester, New York, United States

Site Status

SPARC Site 45

Charlotte, North Carolina, United States

Site Status

SPARC Site 4

Charlotte, North Carolina, United States

Site Status

SPARC Site 24

Greensboro, North Carolina, United States

Site Status

SPARC Site 2

Winston-Salem, North Carolina, United States

Site Status

SPARC Site 75

Winston-Salem, North Carolina, United States

Site Status

SPARC Site 16

Akron, Ohio, United States

Site Status

SPARC Site 33

Centerville, Ohio, United States

Site Status

SPARC Site 56

Columbus, Ohio, United States

Site Status

SPARC Site 12

Eugene, Oregon, United States

Site Status

SPARC Site 44

Springfield, Oregon, United States

Site Status

SPARC Site 68

Abington, Pennsylvania, United States

Site Status

SPARC Site 29

Old Point Station, South Carolina, United States

Site Status

SPARC Site 7

Austin, Texas, United States

Site Status

SPARC Site 71

Dallas, Texas, United States

Site Status

SPARC Site 43

Houston, Texas, United States

Site Status

SPARC Site 13

Salt Lake City, Utah, United States

Site Status

SPARC Site 26

Tacoma, Washington, United States

Site Status

SPARC Site 74

Huntington, West Virginia, United States

Site Status

SPARC Site 69

Milwaukee, Wisconsin, United States

Site Status

SPARC Site 67

Waukesha, Wisconsin, United States

Site Status

SPARC Site 77

Dresden, , Germany

Site Status

SPARC Site 76

Erbach im Odenwald, , Germany

Site Status

SPARC Site 79

Teupitz, , Germany

Site Status

SPARC Site 78

Westerstede, , Germany

Site Status

SPARC Site 82

Budapest, , Hungary

Site Status

SPARC site 83

Budapest, , Hungary

Site Status

SPARC Site 81

Eger, , Hungary

Site Status

SPARC Site 80

Esztergom, , Hungary

Site Status

SPARC Site 87

Moscow, , Russia

Site Status

SPARC Site 86

Novosibirsk, , Russia

Site Status

SPARC Site 85

Saint Petersburg, , Russia

Site Status

SPARC Site 84

Sestroretsk, , Russia

Site Status

SPARC Site 88

Stavropol, , Russia

Site Status

SPARC Site 90

Dnipropetrovsk, , Ukraine

Site Status

SPARC Site 92

Lviv, , Ukraine

Site Status

SPARC Site 91

Poltava, , Ukraine

Site Status

SPARC Site 89

Zaporozh’ye, , Ukraine

Site Status

Countries

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United States Germany Hungary Russia Ukraine

Provided Documents

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Document Type: Study Protocol

View Document

Document Type: Statistical Analysis Plan

View Document

Other Identifiers

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CLR_09_21

Identifier Type: -

Identifier Source: org_study_id

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