Effect of Essential Oils in Aromatherapy on Emotional Relaxation

NCT ID: NCT01443871

Last Updated: 2015-05-27

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 48 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2011-09-30
• Study Completion Date: 2014-12-31

Brief Summary

The purpose of this study is to examine and compare electroencephalography (EEG) changes in human subjects directly after inhalation of essential oils from five Thai aromatherapies. The investigators hypothesize that essential oils from Thai aromatherapies may influence the human EEG involving emotional relaxation particularly alpha wave EEG.

Detailed Description

The subjects consisted of 22 male and 26 female subjects , ages between 20 to 30 years (mean age, 23.3 years). They were screened for excessive nasal congestion, drug and food taken, and neurological disorders prior to participation in the experiment. The experiments were approved by the Ethical Committee for Research Involving Human Research Subject, Naresuan University. All subjects read and signed an informed consent before participation.

Conditions

Healthy

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Blinding Strategy: TRIPLE

Study Groups

Aromatherapy

Experimental procedures were conducted in the morning. Subjects individually entered the closed room where the temperature was kept at 25-26 oC and humidity 50-60%. The subjects were blinded using mask and were seated comfortably with eyes closed during experimental period. The EEG was recorded using silver electrodes. EEG activity was monitored 4 areas (F7, F8, T3 and T4) and ground electrodes. The experiments were divided into 3 parts. The first part, no-odor were recorded EEG activity for 10 minutes as a baseline. The second part, subject was exposure to the odor for 10 minutes as during inhalation. The last part, the odor was dispersed and assessed EEG activity for 10 minutes as after inhalation.

Group Type: EXPERIMENTAL

Aromatherapy

Intervention Type: OTHER

Subject will assigned inhale aromatherapy

Pure water

Experimental procedures were conducted in the morning. Subjects individually entered the closed room where the temperature was kept at 25-26 oC and humidity 50-60%. The subjects were blinded using mask and were seated comfortably with eyes closed during experimental period. The EEG was recorded using silver electrodes. EEG activity was monitored 4 areas (F7, F8, T3 and T4) and ground electrodes. The experiments were divided into 3 parts. The first part, no-odor were recorded EEG activity for 10 minutes as a baseline. The second part, subject was exposure to the water for 10 minutes as during inhalation. The last part, the water was dispersed and assessed EEG activity for 10 minutes as after inhalation.

Group Type: PLACEBO_COMPARATOR

Pure water

Intervention Type: OTHER

Subject will assigned inhale Pure water

Interventions

Aromatherapy

Subject will assigned inhale aromatherapy

Intervention Type: OTHER

Pure water

Subject will assigned inhale Pure water

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• > 18 years old

Exclusion Criteria

• excessive nasal congestion
• neurological disorders prior to participation in the experiment

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 60 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

University of Phayao

OTHER

Sponsor Role: lead

Responsible Party

Surasak Saokaew

Co-Principal Investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Surasak Saokaew, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Phayao

Locations

Surasak Saokaew

Muang, Changwat Phayao, Thailand

University of Phayao

Muang, Changwat Phayao, Thailand

Countries

Thailand

Other Identifiers

WP-5102031

Identifier Type: -

Identifier Source: org_study_id