Ex Vivo Evaluation of the Interest of the Association of Platinum With a Molecule BH3-mimetic ABT-737 in Samples of Ovarian Tumors

NCT ID: NCT01440504

Last Updated: 2013-02-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

36 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-04-30

Study Completion Date

2013-01-31

Brief Summary

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The aim of the study is to quantify the ex vivo induction of apoptosis by ABT-737 + association platinum in samples exposed and demonstrate the value of this combination compared to the agents used alone.

Detailed Description

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Conditions

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Ovarian Cancer

Study Design

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Study Time Perspective

PROSPECTIVE

Interventions

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culture ex vivo with exposure to different therapeutic agents alone or in combination.

When tumor resection, tumor specimens of ovarian cancer will be made towards a culture ex vivo with exposure to different therapeutic agents alone or in combination.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patient aged over 18 years
* Ovarian cancer patients with at least five tumor samples does not affect the diagnosis, based on other tumor masses
* Surgery of any initial chemotherapy naive
* Patient information and signed informed consent

Exclusion Criteria

* A person deprived of liberty or under guardianship
* Insufficient tumor samples of ovarian cancer.
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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GRECAN

UNKNOWN

Sponsor Role collaborator

Centre Francois Baclesse

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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JOLY Florence, Pr

Role: PRINCIPAL_INVESTIGATOR

Centre françois Baclesse

Locations

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Centre François Baclesse

Caen, , France

Site Status

Countries

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France

Other Identifiers

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ABT-737 ex vivo

Identifier Type: -

Identifier Source: org_study_id

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