Gastrointestinal Microcirculation During Cardiopulmonary Bypass

NCT ID: NCT01425931

Last Updated: 2014-08-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-06-30

Study Completion Date

2014-08-31

Brief Summary

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O2C is a diagnostic device for non-invasive determination of oxygen supply in microcirculation of blood perfused tissues. The optical sensor is easy to handle and guarantees reproducible examinations of local oxygen supply of tissues in clinics as well as in research. The examinations are without any strain for your patient.

Determines by use of a glass fibre probe:

Blood Flow in Microcirculation Capillary-Venous Oxygen Saturation Blood Filling of Microvessels Blood Flow Velocity This device makes it possible to supervise the local oxygen supply of organs and tissue.

With it is possible to measure locally the amount of oxygen which is transported into the region of interest and to diagnose local oxygen consumption of an organ. O2C's novelty is monitoring the energetic metabolism of cells by measuring the oxygen uptake with an optical sensor probe. Pathological O2-supply, which can lead to angiogenesis or cell-death and subsequently to organ failure, now can be detected in an early state by use of the new sensor system.

One of these new developed sensors are used to place in rectal position during extracorporeal circulation to determine the microcirculation.

Detailed Description

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Conditions

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MeSH Heading Cardiac Surgical Procedures Tree Number E04.100.376 Tree Number E04.928.220

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Extracorporeal circulation

all patients were measured by microcirculation device O2C

Heart Lung machine

Intervention Type PROCEDURE

measurement of microcirculation with O2C device

Interventions

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Heart Lung machine

measurement of microcirculation with O2C device

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients on extracorporeal circulation

Exclusion Criteria

* Haemorrhoidal lesions
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Johann Wolfgang Goethe University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Arndt-H. Kiessling

Head cardiovascular research

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Goethe University

Frankfurt am Main, Hesse, Germany

Site Status

Countries

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Germany

Other Identifiers

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O2C-001AHK

Identifier Type: -

Identifier Source: org_study_id

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