Target Site Pharmacokinetics of Doripenem at Steady State in Intubated Intensive Care Patients

NCT ID: NCT01414959

Last Updated: 2017-08-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

16 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-08-31

Study Completion Date

2013-07-31

Brief Summary

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The investigators will measure the pharmacokinetics of doripenem in skeletal muscle, subcutaneous adipose tissue, bronchoalveolar lavage and plasma of intubated intensive care patients.

Detailed Description

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Methods: microdialysis, blood sampling, bronchoalveolar lavage

Conditions

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Pneumonia Abdominal Infection Urinary Tract Infection

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* endotracheal intubation; pneumonia or complicated abdominal infection or complicated urinary tract infection

Exclusion Criteria

* allergy to doripenem, hemodialysis
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medical University of Vienna

OTHER

Sponsor Role lead

Responsible Party

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Markus Zeitlinger

Professor Dr.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Markus Zeitlinger, MD

Role: PRINCIPAL_INVESTIGATOR

Medical Universit of Vienna

Locations

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Med. Univ. of Vienna

Vienna, , Austria

Site Status

Countries

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Austria

Other Identifiers

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Dori_MD_ICU

Identifier Type: -

Identifier Source: org_study_id

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