Impact of Continuous Positive Airway Pressure on the Treatment of Acute Asthma Exacerbation

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

86 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-04-30

Study Completion Date

2011-01-31

Brief Summary

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This current study aimed to demonstrate the effectiveness of the addition of CPAP to the current conventional therapy in terms of airway obstruction improvement in acute asthma patients.

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Detailed Description

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Continuous positive airway pressure (CPAP) is widely used in providing ventilator support. However, its role in an acute asthmatic attack is uncertain. The purpose of this study was to compare the efficacy of CPAP when used in addition to conventional therapy with conventional therapy alone in the management of acute asthma exacerbation.

Conditions

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Acute Asthma

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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NIPPV

Group Type EXPERIMENTAL

Continuous positive airway pressure

Intervention Type DEVICE

CPAP 8 cmH2O

Interventions

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Continuous positive airway pressure

CPAP 8 cmH2O

Intervention Type DEVICE

Other Intervention Names

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GoodKnight 420 G; Nellcor Puritan Bennett Inc.

Eligibility Criteria

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Inclusion Criteria

* aged over 18 years
* known asthmatic patients visiting ED with acute exacerbation
* had given their written informed consent.

Exclusion Criteria

* smoking history
* chronic obstructive pulmonary disease
* required intubation
* instability of hemodynamic or arrhythmia
* unable to perform PEFR
* facial abnormality
* pulmonary infiltration
* pregnancy.

Minimum Eligible Age

19 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No