A Study of a Novel Silicone Dressing to Minimize Scar Formation

NCT ID: NCT01399099

Last Updated: 2024-11-19

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

67 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-06-30

Study Completion Date

2013-03-31

Brief Summary

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Neodyne has developed an investigational dressing for post-operative incision care. Neodyne is conducting this research to study whether the investigational dressing, called the Neodyne Dressing, can minimize scar formation in a simple manner.

Detailed Description

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It is proposed to study a dressing designed to reduce scarring in post-incision skin tissue. It is expected that by managing the incision site during the healing phase, scar formation may be minimized.

Conditions

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Hypertrophic

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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embrace Dressing

Investigational Dressing

Group Type EXPERIMENTAL

embrace device

Intervention Type DEVICE

Adhesive bandage/dressing intended to minimize scar formation.

Standard of Care

Standard of care comparator

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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embrace device

Adhesive bandage/dressing intended to minimize scar formation.

Intervention Type DEVICE

Other Intervention Names

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Neodyne Device embrace dressing Neodyne Dressing

Eligibility Criteria

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Inclusion Criteria

* Subjects who have undergone a de novo abdominoplasty.
* Appearance of subject's incision is aesthetically similar across length of incision.

Exclusion Criteria

* Subjects with a history of collagen vascular disease, cutis laxica, connective tissue disease, psoriasis, or lupus.
* Subjects diagnosed with scleroderma.
* Subjects with known adverse reactions to steri-strip tapes, medical tapes, or adhesives.
* Subjects with oozing, dehiscence, non-closed/healed incisions at time of first application.
* Subjects with inability to maintain adequate care of incision.
* Subjects with a body mass index (BMI) \> 30.
* Subjects with a weight loss of greater than or equal to 100 lbs within 6 months from date of abdominoplasty.
* Subjects who currently smoke.
* Subjects taking steroid therapy.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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U.S. Army Medical Research and Development Command

FED

Sponsor Role collaborator

Neodyne Biosciences, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Rodney J Rohrich, MD, FACS

Role: PRINCIPAL_INVESTIGATOR

University of Texas Southwestern Medical Center

Locations

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Atherton Plastic Surgery

Atherton, California, United States

Site Status

Vipul R. Dev MD

Bakersfield, California, United States

Site Status

Elite MD

Danville, California, United States

Site Status

Kaufman and Clark Plastic Surgery

Folsom, California, United States

Site Status

The Aesthetic Institute

Fullerton, California, United States

Site Status

The Korman Group

Mountain View, California, United States

Site Status

Newport Plastic Surgery

Newport Beach, California, United States

Site Status

Lauren Greenberg, MD

Palo Alto, California, United States

Site Status

Plastic Surgery Associates of Santa Rose

Santa Rosa, California, United States

Site Status

Joseph Mele, MD

Walnut Creek, California, United States

Site Status

Academy of Clinical Research

Arlington, Texas, United States

Site Status

The University of Texas Southwestern Medical Center - Dept. of Plastic Surgery

Dallas, Texas, United States

Site Status

US Army Institute of Surgical Research

Fort Sam Houston, Texas, United States

Site Status

Countries

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United States

References

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Longaker MT, Rohrich RJ, Greenberg L, Furnas H, Wald R, Bansal V, Seify H, Tran A, Weston J, Korman JM, Chan R, Kaufman D, Dev VR, Mele JA, Januszyk M, Cowley C, McLaughlin P, Beasley B, Gurtner GC. A randomized controlled trial of the embrace advanced scar therapy device to reduce incisional scar formation. Plast Reconstr Surg. 2014 Sep;134(3):536-546. doi: 10.1097/PRS.0000000000000417.

Reference Type DERIVED
PMID: 24804638 (View on PubMed)

Other Identifiers

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00016580

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

CA003

Identifier Type: -

Identifier Source: org_study_id

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