The SeriScaffold® Use in Reconstruction Post Market Study for Tissue Support and Repair in Breast Reconstruction Surgery in Europe

NCT ID: NCT01389232

Last Updated: 2021-06-21

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

104 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-06-30

Study Completion Date

2015-02-28

Brief Summary

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This is a post-market study of the use of SeriScaffold® for soft tissue support and repair in breast reconstruction surgery.

Detailed Description

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Conditions

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Soft Tissue Support and Repair

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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SeriScaffold® Surgical Scaffold

Participants with breast reconstruction surgery implanted with SERI® Surgical Scaffold.

Group Type EXPERIMENTAL

SeriScaffold® Surgical Scaffold

Intervention Type DEVICE

A CE Marked, 510(k) cleared, knitted, multi-filament, bioengineered, silk mesh indicated for use as a transitory scaffold for soft tissue support and repair

Interventions

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SeriScaffold® Surgical Scaffold

A CE Marked, 510(k) cleared, knitted, multi-filament, bioengineered, silk mesh indicated for use as a transitory scaffold for soft tissue support and repair

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Be female, greater or equal to 18 years of age
* Be willing to undergo immediate breast reconstruction with sub-pectoralis muscle placement of a breast implant
* Be willing to undergo mastectomy with healthy, well vascularized skin flaps anticipated by the surgeon
* Be in good health other than breast pathology and be suited to general anesthesia and planned treatments

Exclusion Criteria

* Have undergone breast radiation treatment and/or is preoperatively evaluated to require radiation treatment to the breast area during the course of the study
* Have a known allergy to silk
* Have any disease, including uncontrolled diabetes, which is clinically known to impact wound healing ability
* Have undergone previous breast surgery with the exception of mastectomy, breast biopsy, cyst removal, lumpectomy, mastopexy, reduction and/or augmentation
* Have had a prior soft tissue support device implanted in the breast
* Have a condition or be in a situation that, in the Investigator's opinion, may put the subject at significant risk, may confound the study results, or may interfere significantly with the subject's participation in the study
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Sofregen Medical, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Düsseldorf, , Germany

Site Status

Munich, , Germany

Site Status

Milan, , Italy

Site Status

Barcelona, , Spain

Site Status

Nottingham, , United Kingdom

Site Status

Countries

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Germany Italy Spain United Kingdom

Other Identifiers

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SURE-002

Identifier Type: -

Identifier Source: org_study_id

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