The Telomere System in Cord Blood and in the Placenta in High Risk Pregnancies

NCT ID: NCT01384136

Last Updated: 2011-06-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-06-30

Study Completion Date

2015-06-30

Brief Summary

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The telomere system stabilizes the chromosomes. Telomeres are shortened during senescence, in cases of genetic instability and secondary to stress.

The investigators aim is to study the telomere system in cord blood and in the placenta immediately after the delivery in pregnancies defined as high risk pregnancies following sterss events such as placental insufficiency, preeclampsia, diabetes.

The investigators intend to compare the telomere system in maternal blood to cord blood and to placental biopsies and to study the influence of different stressogenes on this system.

Detailed Description

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Conditions

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Telomere Length Mechanisms of Telomter Homeostasis High Risk Pregnancies

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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High risk pregnancy

No interventions assigned to this group

|Control - Normal low risk pregnancies

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Third trimester post delivery
* Intrauterine growth restriction
* Preeclampsia
* Diabetes
* Control - low risk normal pregnancies

Exclusion Criteria

* Patients who do not want to participate
* Known HIV or Hepatitis
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Meir Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Meir Medical Center, Kfar Saba, Israel

Locations

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Meir Medical Center

Kfar Saba, , Israel

Site Status

Countries

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Israel

Other Identifiers

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036-2011 MMC

Identifier Type: -

Identifier Source: org_study_id

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