Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
15 participants
OBSERVATIONAL
2009-08-31
2010-12-31
Brief Summary
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* A breath collection apparatus for collection of volatile organic compounds in breath onto a sorbent trap and Tedlar bag, as well as for the collection of a separate sample of room air.
* Analysis of the volatile organic compounds in breath and room air by short acoustic wave/gas chromatography.
* Interpretation of the volatile organic compounds with a proprietary algorithm in order to predict the probability of lower respiratory tract colonization and infection.
* Analysis of the volatile organic compounds in sputum culture by short acoustic wave/gas chromatography.
This study will test the hypothesis that the investigators can identify the presence of mycobacteria in an individual by sampling the breath of patients with active tuberculosis and by sampling "head space" above culture media of sputum provided. This study will test the hypotheses:
* that the investigators can identify positive cultures for mycobacterium tuberculosis through sampling of the headspace above the cultures prior to standard laboratory culture identification
* that the investigators can identify control of tuberculosis by sampling exhaled breath
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Tuberculosis Patients
Suspected Tuberculosis patients
No interventions assigned to this group
Control
Healthy volunteers
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* Positive tuberculosis skin test
* Positive sputum culture for TB
* X-rays indicated possible tuberculosis infection or disease
* ability to give breath and sputum samples at regular intervals
Exclusion Criteria
* History of or active pulmonary disease other than tuberculosis
1 Year
40 Years
ALL
Yes
Sponsors
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Landon Pediatric Foundation
OTHER
Responsible Party
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Locations
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Oxnard Specialty Clinic
Oxnard, California, United States
Pediatric Diagnostic Center
Ventura, California, United States
Countries
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Other Identifiers
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TB1
Identifier Type: -
Identifier Source: org_study_id
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