The Effect of the Duty Loading on the Stress Response of Physician

NCT ID: NCT01367379

Last Updated: 2012-01-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

15 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-06-30

Study Completion Date

2012-12-31

Brief Summary

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The investigators will study in the possibility of cardiovascular disease, caused by the duty loading, of physician of internal medicine. The investigators will also explore if there {dose response effect} between the duty loading and the stress response of physicians of internal medicine. Therefore, the investigators will compare the stress responses of physicians of internal medicine during with different duty loading ( non-duty day, one duty area with 3 wards, 2 duty areas with 6 wards) in a observational method. Those stress response will be measured by cardiovascular risk indicators, including blood pressure, heart rate variability, blood sampling and urine sampling.

Detailed Description

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Conditions

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Physiological Stress Psychological Stress

Study Design

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Observational Model Type

CASE_CROSSOVER

Study Time Perspective

PROSPECTIVE

Study Groups

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Physician of internal medicine in Taipei city hospital

24 hour EKG and blood pressure monitor

Intervention Type PROCEDURE

All subjects will have non-invasive 24 hour EKG and 24 hour EKG monitoring for 24 hours.

Blood and urine sampling

Intervention Type OTHER

Right before and after the duty loading, all subjects will have blood samplings, including CRP, WBC, IL-6, Fibrinogen, insulin, IL-6, Procalcitonin, TNF-alfa, catecholamine level. Right after the duty loading, all subjects will have urine samplings for cortisol and catecholamine level.(blood : 15CC/time and 2\~4 times/month)

Interventions

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24 hour EKG and blood pressure monitor

All subjects will have non-invasive 24 hour EKG and 24 hour EKG monitoring for 24 hours.

Intervention Type PROCEDURE

Blood and urine sampling

Right before and after the duty loading, all subjects will have blood samplings, including CRP, WBC, IL-6, Fibrinogen, insulin, IL-6, Procalcitonin, TNF-alfa, catecholamine level. Right after the duty loading, all subjects will have urine samplings for cortisol and catecholamine level.(blood : 15CC/time and 2\~4 times/month)

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Attending physicians of internal medicine of Taipei municipal hospital, certified by Taiwan society of internal medicine.

Exclusion Criteria

* thyroid dysfunction
* pregnancy, diabetes mellitus
* history of cardiovascular disease (stroke, coronary arterial disease, or myocardial infraction)
* current smokers, or
* taking sleeping pills or B-blocker
Minimum Eligible Age

30 Years

Maximum Eligible Age

60 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Taipei City Hospital

OTHER_GOV

Sponsor Role collaborator

National Taiwan University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Yue Leon Guo, Professor

Role: PRINCIPAL_INVESTIGATOR

National Taiwan University Hospital

Locations

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National Taiwan university hospital

Taipei, , Taiwan

Site Status RECRUITING

Countries

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Taiwan

Central Contacts

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Hsiu Hao Lee, MD

Role: CONTACT

886-2-25523234 ext. 5540

Facility Contacts

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Hsiu Hao Lee, MD

Role: primary

886-25523234 ext. 5540

Other Identifiers

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201104059RC

Identifier Type: -

Identifier Source: org_study_id

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