Multicenter Study to Investigate SER120 Nasal Spray Formulations in Patients With Nocturia

NCT ID: NCT01357356

Last Updated: 2020-10-08

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2/PHASE3

Total Enrollment

750 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-05-31

Study Completion Date

2014-12-31

Brief Summary

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The purpose of this study is to investigate the efficacy and safety of SER120 nasal spray formulations in patients with nocturia for a total duration of 14 weeks.

Detailed Description

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Conditions

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Nocturia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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SER120 (750 ng/day)

SER120 (750 ng/day)

Group Type EXPERIMENTAL

SER120 (750 ng/day)

Intervention Type DRUG

SER120 (1000 ng/day)

SER120 (1000 ng/day)

Group Type EXPERIMENTAL

SER120 (1000 ng/day)

Intervention Type DRUG

SER120 (1000 ng/day)

SER120 (1500 ng/day)

SER120 (1500 ng/day)

Group Type EXPERIMENTAL

SER120 (1500 ng/day)

Intervention Type DRUG

Placebo

Placebo

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DRUG

Interventions

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SER120 (750 ng/day)

Intervention Type DRUG

SER120 (1000 ng/day)

SER120 (1000 ng/day)

Intervention Type DRUG

SER120 (1500 ng/day)

Intervention Type DRUG

Placebo

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Male and female 50 years or older
* Nocturia of 6 or more months duration averaging greater than 2 nocturic episode per night

Exclusion Criteria

* CHF
* Diabetis Insipidus
* Renal Insufficiency
* Hepatic Insufficiency
* Incontinence
* Illness requiring systemic steroids
* Malignancy within the past 5 years
* Sleep Apnea
* Nephrotic Syndrome
* Unexplained Pelvic Mass
* Urinary Bladder Neurological dysfunction
* Urinary Bladder Surgery or Radiotherapy
* Pregnant or Breast Feeding
Minimum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Serenity Pharmaceuticals, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Serenity R&D

New City, New York, United States

Site Status

Countries

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United States

Other Identifiers

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SPC-SER120-DB3-201101

Identifier Type: -

Identifier Source: org_study_id

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