Effects of Plant Extracts on Semen Quality

NCT ID: NCT01357044

Last Updated: 2014-10-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

70 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-05-31

Study Completion Date

2013-07-31

Brief Summary

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this is a prospective randomized placebo-controlled double-blinded trial investigating the effect of plant extracts from Alpinia galanga and Punica granatum on human semen quality. The investigators hypothesize that these plant extracts will improve semen quality.

Detailed Description

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Conditions

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Poor Semen Quality

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Plant extracts

Group Type ACTIVE_COMPARATOR

Extracts of Punica granatum and Alpinia galanga

Intervention Type DIETARY_SUPPLEMENT

Tablets, two in the morning and two in the evening

Placebo

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DIETARY_SUPPLEMENT

Tablets, two in the morning and two in the evening

Interventions

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Extracts of Punica granatum and Alpinia galanga

Tablets, two in the morning and two in the evening

Intervention Type DIETARY_SUPPLEMENT

Placebo

Tablets, two in the morning and two in the evening

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Reduced semen quality

Exclusion Criteria

* Total count of motile sperm less than 1 million sperm/ejaculate or more than 200 million sperm/ejaculate
Minimum Eligible Age

18 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Videns- og Forskningscenter for Alternativ Behandling

OTHER

Sponsor Role collaborator

Horsens Hospital

OTHER

Sponsor Role lead

Responsible Party

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Jens Fedder

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Laboratory of Reproductive Biology

Horsens, , Denmark

Site Status

Countries

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Denmark

References

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Fedder MD, Jakobsen HB, Giversen I, Christensen LP, Parner ET, Fedder J. An extract of pomegranate fruit and galangal rhizome increases the numbers of motile sperm: a prospective, randomised, controlled, double-blinded trial. PLoS One. 2014 Oct 2;9(9):e108532. doi: 10.1371/journal.pone.0108532. eCollection 2014.

Reference Type DERIVED
PMID: 25275520 (View on PubMed)

Other Identifiers

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LRB-SU-010

Identifier Type: -

Identifier Source: org_study_id

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