Costimulatory Molecules as Biomarkers in Cystic Fibrosis

NCT ID: NCT01353950

Last Updated: 2017-04-06

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 40 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2011-07-31
• Study Completion Date: 2013-06-30

Brief Summary

The purpose of this study is to investigate the expression of a certain class of molecules, called costimulatory molecules, in humans with Cystic Fibrosis. Cystic Fibrosis is a genetic disorder which renders the lung susceptible to persistent inflammation which, at times, can worsen, resulting in accelerated decline in lung function and eventually death or transplant. Our goal is to determine if the levels of costimulatory markers can be used to predict exacerbation and subsequent lung function decline in subjects with Cystic Fibrosis.

Conditions

Cystic Fibrosis

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

Adult Cystic Fibrosis Patients

Adults with Cystic Fibrosis will be followed longitudinally for 2 years

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• Willingness to participate

Exclusion Criteria

• Presence of HIV
• Presence of Lymphoma/Leukemia
• Presence of Lung or other solid organ Transplant
• Pregnancy

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 80 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Oregon Health and Science University

OTHER

Sponsor Role: lead

Responsible Party

Jeffrey Gold

professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Oregon health and Sciences University

Portland, Oregon, United States

Countries

United States

Other Identifiers

IRB00007132

Identifier Type: -

Identifier Source: org_study_id