Single Port Laparoscopic Cholecystectomy Versus Four Port Laparoscopic Cholecystectomy: Impact on Postoperative Pain

NCT ID: NCT01348620

Last Updated: 2011-05-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

58 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-03-31

Brief Summary

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This is a single-institution, prospective, randomized controlled trial. Subjects determined to need a cholecystectomy will be consented for surgery and study participation prior to enrollment in this study. Patients will then be randomized to receive either a single port laparoscopic cholecystectomy or a four port laparoscopic cholecystectomy.

Detailed Description

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The main advantages of laparoscopic surgery are reduced postoperative pain, shorter hospital stay and the cosmetic result. Although reduced, however, pain is still substantial and constitutes the main clinical problem after laparoscopic cholecystectomy, in particular for future daily planned procedures.

Recently, a new technique of laparoscopic cholecystectomy has been developed, in which all instruments are inserted through the same port placed in the umbilical incision. This technique for cholecystectomy has been proved to be feasible and safe by several studies.

The purpose of the study is to compare postoperative pain, operating time, cosmetic result, between one port and standard laparoscopic cholecystectomy.

Conditions

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Postoperative Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Single port laparoscopic device

Group Type EXPERIMENTAL

Single port laparoscopic cholecystectomy SINGLE SITE LAPAROSCOPY ACCESS SYSTEM (Johnson & Johnson Medical Spa)

Intervention Type DEVICE

Single port laparoscopic cholecystectomy. SINGLE SITE LAPAROSCOPY ACCESS SYSTEM (Johnson \& Johnson Medical Spa)

Four-port laparoscopic device

Group Type ACTIVE_COMPARATOR

Four port laparoscopic cholecystectomy surgery

Intervention Type PROCEDURE

Four port laparoscopic cholecystectomy surgery

Interventions

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Single port laparoscopic cholecystectomy SINGLE SITE LAPAROSCOPY ACCESS SYSTEM (Johnson & Johnson Medical Spa)

Single port laparoscopic cholecystectomy. SINGLE SITE LAPAROSCOPY ACCESS SYSTEM (Johnson \& Johnson Medical Spa)

Intervention Type DEVICE

Four port laparoscopic cholecystectomy surgery

Four port laparoscopic cholecystectomy surgery

Intervention Type PROCEDURE

Other Intervention Names

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One-trocar cholecistectomy traditional Laparoscopic cholecistectomy

Eligibility Criteria

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Inclusion Criteria

* Biliary cholic
* Biliary dyskinesia
* Gallbladder polyps
* Other diagnosis at the discretion of the surgeon

Exclusion Criteria

* History of Acute cholecystitis
* Jaundice
* Choledocolithiasis
* History of Pancreatitis
* Severe comorbidity
* BMI \> 30
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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IRCCS Sacro Cuore Don Calabria di Negrar

OTHER

Sponsor Role lead

Responsible Party

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Sacro Cuore Don Calabria General Hospital

Locations

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Sacro Cuore - Don Calabria Hospital

Negrar, Verona, Italy

Site Status RECRUITING

Countries

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Italy

Central Contacts

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Giuliano Barugola, MD

Role: CONTACT

00390456013111

Facility Contacts

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Giuliano Barugola, MD

Role: primary

References

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Rao PP, Bhagwat SM, Rane A, Rao PP. The feasibility of single port laparoscopic cholecystectomy: a pilot study of 20 cases. HPB (Oxford). 2008;10(5):336-40. doi: 10.1080/13651820802276622.

Reference Type BACKGROUND
PMID: 18982149 (View on PubMed)

Hirano Y, Watanabe T, Uchida T, Yoshida S, Tawaraya K, Kato H, Hosokawa O. Single-incision laparoscopic cholecystectomy: single institution experience and literature review. World J Gastroenterol. 2010 Jan 14;16(2):270-4. doi: 10.3748/wjg.v16.i2.270.

Reference Type BACKGROUND
PMID: 20066749 (View on PubMed)

Tacchino R, Greco F, Matera D. Single-incision laparoscopic cholecystectomy: surgery without a visible scar. Surg Endosc. 2009 Apr;23(4):896-9. doi: 10.1007/s00464-008-0147-y. Epub 2008 Sep 25.

Reference Type BACKGROUND
PMID: 18815836 (View on PubMed)

Gumbs AA, Milone L, Sinha P, Bessler M. Totally transumbilical laparoscopic cholecystectomy. J Gastrointest Surg. 2009 Mar;13(3):533-4. doi: 10.1007/s11605-008-0614-8.

Reference Type BACKGROUND
PMID: 18709515 (View on PubMed)

Kuon Lee S, You YK, Park JH, Kim HJ, Lee KK, Kim DG. Single-port transumbilical laparoscopic cholecystectomy: a preliminary study in 37 patients with gallbladder disease. J Laparoendosc Adv Surg Tech A. 2009 Aug;19(4):495-9. doi: 10.1089/lap.2008.0424.

Reference Type BACKGROUND
PMID: 19630589 (View on PubMed)

Partelli S, Barugola G, Sartori A, Crippa S, Falconi M, Ruffo G. Single-incision laparoscopic cholecystectomy versus traditional laparoscopic cholecystectomy performed by a single surgeon: findings of a randomized trial. Surg Today. 2016 Mar;46(3):313-8. doi: 10.1007/s00595-015-1182-7. Epub 2015 Jun 3.

Reference Type DERIVED
PMID: 26036221 (View on PubMed)

Steinemann DC, Raptis DA, Lurje G, Oberkofler CE, Wyss R, Zehnder A, Lesurtel M, Vonlanthen R, Clavien PA, Breitenstein S. Cosmesis and body image after single-port laparoscopic or conventional laparoscopic cholecystectomy: a multicenter double blinded randomised controlled trial (SPOCC-trial). BMC Surg. 2011 Sep 12;11:24. doi: 10.1186/1471-2482-11-24.

Reference Type DERIVED
PMID: 21910897 (View on PubMed)

Other Identifiers

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MNT-2011

Identifier Type: -

Identifier Source: org_study_id

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