The Effect of Vitamin c on Preventing Complex Regional Pain Syndrome (CRPS Type I) Following Ankle Fracture

NCT ID: NCT01338129

Last Updated: 2011-04-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-04-30

Study Completion Date

2014-02-28

Brief Summary

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The use of prophylactic treatment with vitamin c may prevent complex regional pain syndrome (CRPS)

Detailed Description

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There are several studies similar in wrist fracture.

Conditions

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Ankle Fracture

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

TRIPLE

Participants Caregivers Investigators

Study Groups

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vitamin c

administration of vitamin c for 45 days following ankle fracture operation

Group Type EXPERIMENTAL

vitamin c

Intervention Type DIETARY_SUPPLEMENT

1000 mg of vitamin c for 45 days

placebo

placebo pills

Group Type PLACEBO_COMPARATOR

placebo

Intervention Type DRUG

placebo pills

Interventions

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vitamin c

1000 mg of vitamin c for 45 days

Intervention Type DIETARY_SUPPLEMENT

placebo

placebo pills

Intervention Type DRUG

Other Intervention Names

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ascorbic acid

Eligibility Criteria

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Inclusion Criteria

* ankle fracture within 3 weeks after the fracture

Exclusion Criteria

* pregnant or lactating woman
* open fracture
* already treated with vitamin c
* chronic renal failure
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Rabin Medical Center

OTHER

Sponsor Role lead

Responsible Party

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rabin medical center

Locations

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Beilinson, Rabin Medical Center,

Petah Tikva, Israel, Israel

Site Status

Countries

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Israel

Central Contacts

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alon burg, MD

Role: CONTACT

972-54-4854248

eli sidon, MD

Role: CONTACT

972-52-3896169

Other Identifiers

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RMC116131CTIL

Identifier Type: -

Identifier Source: org_study_id

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