Study of Human Central Nervous System Stem Cells (HuCNS-SC) in Patients With Thoracic Spinal Cord Injury
NCT ID: NCT01321333
Last Updated: 2015-06-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE1/PHASE2
12 participants
INTERVENTIONAL
2011-03-31
2015-04-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
TREATMENT
NONE
Study Groups
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HuCNS-SC cells
Single dose intramedullary administration of HuCNS-SC cells
HuCNS-SC cells
single dose intramedullary transplantation of HuCNS-SC cells in the thoracic spinal cord
Interventions
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HuCNS-SC cells
single dose intramedullary transplantation of HuCNS-SC cells in the thoracic spinal cord
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* T2-T11 thoracic spinal cord injury as assessed by magnetic resonance imaging (MRI) and/or computerized tomography (CT)
* ASIA Impairment Scale (AIS) Grade A, B, or C
* Minimum of six weeks post injury for the initiation of screening
* Must have evidence of preserved conus function
* Must be at stable stage of medical recovery after injury
Exclusion Criteria
* Penetrating spinal cord injury
* Evidence of spinal instability or persistent spinal stenosis and/or compression related to initial trauma
* Previous organ, tissue or bone marrow transplantation
* Previous participation in any gene transfer or cell transplant trial
* Current or prior malignancy
18 Years
60 Years
ALL
No
Sponsors
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StemCells, Inc.
INDUSTRY
Responsible Party
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Principal Investigators
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Stephen Huhn, MD
Role: STUDY_CHAIR
StemCells, Inc.
Locations
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Foothills Medical Center
Calgary, Alberta, Canada
Toronto Western Hospital
Toronto, Ontario, Canada
University Hospital Balgrist- Uniklinik Balgrist, Forschstrasse 340
Zurich, Canton of Zurich, Switzerland
Countries
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Related Links
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Click here for more information on this study
Other Identifiers
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CL-N02-SC
Identifier Type: -
Identifier Source: org_study_id
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