Neoadjuvant Chemotherapy for Locally Advanced Thymic Cancer

NCT ID: NCT01312324

Last Updated: 2016-04-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

27 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-02-28

Study Completion Date

2016-03-31

Brief Summary

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We try to evaluate whether neoadjuvant docetaxel plus cisplatin can increase the complete resection rate in advanced thymic carcinoma.

Detailed Description

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Conditions

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Locally Advanced Stage III or IV Thymic Cancer

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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neoadjuvant chemotherapy

3 cycles of docetaxel/cisplatin before operation

Group Type EXPERIMENTAL

neoadjuvant docetaxel/cisplatin

Intervention Type DRUG

3 cycles of docetaxel plus cisplatin docetaxel 75mg/m2 D1 cisplatin 75mg/m2 D1 every 3 weeks

Interventions

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neoadjuvant docetaxel/cisplatin

3 cycles of docetaxel plus cisplatin docetaxel 75mg/m2 D1 cisplatin 75mg/m2 D1 every 3 weeks

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* histologically confirmed thymic carcinoma
* surgically inoperable Masaoka stage III or IV
* ECOG 0-2
* at least one measurable disease

Exclusion Criteria

* previous myocardiac infarct history within 1 year before the enrollment.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Samsung Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Keunchil Park

Principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Samsung Medical Center

Seoul, , South Korea

Site Status

Countries

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South Korea

Other Identifiers

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2007-01-040

Identifier Type: -

Identifier Source: org_study_id

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