A Study on the Effects of Soulera Herbal Blend Intake on Chronic Stress in Healthy Adults

NCT ID: NCT01299402

Last Updated: 2012-10-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

PHASE1

Total Enrollment

64 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-08-31

Study Completion Date

2012-09-30

Brief Summary

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The purpose of the study was designed to evaluate the efficacy and safety of Soulera herbal mix in powder form and its effects on anxiety and the biomarkers for chronic stress.

Detailed Description

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Conditions

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Chronic Stress

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Soulera Herbal Blend

Group Type EXPERIMENTAL

Soulera Herbal Blend

Intervention Type DIETARY_SUPPLEMENT

This a powder blend of various reputed adaptogenic herbs. The dosage will be one 8.6 gram powder sachet daily.

Placebo Blend

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DIETARY_SUPPLEMENT

The placebo will be a similar tasting and looking powder blend as the Soulera Herbal Blend. The dosage will be 8.6 grams per sachet daily.

Interventions

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Soulera Herbal Blend

This a powder blend of various reputed adaptogenic herbs. The dosage will be one 8.6 gram powder sachet daily.

Intervention Type DIETARY_SUPPLEMENT

Placebo

The placebo will be a similar tasting and looking powder blend as the Soulera Herbal Blend. The dosage will be 8.6 grams per sachet daily.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Healthy men and women between the ages of 21-65.
* No concerns that would confound the study as determined by study physicians.
* Women must not be pregnant or become pregnant for the duration of the study.

Exclusion Criteria

* The subject has a history of hypersensitivity to any of the compounds used in the study
* The subject is pregnant or breast feeding. Note: If the potential subject is a post-menarche female, a urine pregnancy test must be performed within 24 hours prior to study drug administration and confirmed negative in order for the potential subject to eb enrolled.
* History of Psychiatric Illness or Chronic Stress or Anxiety
* Hypertension, cardiovascular disease, liver, hypokalemia, or kidney disease or other health concerns that the study physician feels may confound study results
* Individuals who are cognitively impaired or who are not able to give informed consent
* Any routine prescription medication that the study physician feels may cause drug interaction with Soulera or alter the prescription medications' activity
* Previous participation in a clinical research trial within 30 days prior to randomization
* The subject has an ongoing abuse of illicit substances, alcohol, or actively smoking marijuana
* The subject uses or has used in the past 30 days any steroid formulation, be it topical like face cream, ocular as in an eye drop, nasal as in a spray, injection or pill.
* The subject is a current smoker or uses tobacco products such as chewing tobacco.
* The subject is actively engaging in the use of Herbal Medicine, Traditional Chinese Medicine, Ancient Indian Medicine, Yoga, or Ayurveda
* The subject is a night-shift worker and therefore presumably has an altered cortisol diurnal rhythm and is also unable to comply with the required cortisol collection times of the study
Minimum Eligible Age

21 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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LeraPharm Inc.

INDUSTRY

Sponsor Role collaborator

Joseph Pergolizzi, MD

INDUSTRY

Sponsor Role lead

Responsible Party

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Joseph Pergolizzi, MD

Principal Investigator

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Joseph V Pergolizzi, Jr., M.D.

Role: PRINCIPAL_INVESTIGATOR

NEMA Research, Inc.

Robert Taylor Jr., Ph.D.

Role: PRINCIPAL_INVESTIGATOR

NEMA Research, Inc.

Ismail Shalaby, M.D., Ph.D.

Role: STUDY_DIRECTOR

NEMA Research, Inc.

Locations

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NEMA Research, Inc.

Naples, Florida, United States

Site Status

Countries

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United States

Related Links

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Other Identifiers

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Adaptogen Study 002

Identifier Type: -

Identifier Source: org_study_id