Hydroxypropylmethylcellulose 0.3% and Sodium Hyaluronate 0.18% for Ocular Surface Disease in Glaucoma

NCT ID: NCT01284439

Last Updated: 2011-01-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-01-31

Study Completion Date

2012-02-29

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

To study effect of hydroxypropylmethylcellulose 0.3% and sodium hyaluronate 0.18% in the treatment of ocular surface disease in glaucoma patients.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Ocular Surface Disease Glaucoma

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

TearA

Group Type EXPERIMENTAL

hydroxypropylmethylcellulose

Intervention Type DRUG

TearA: QID to every 2 hous , 1-2 drops per each time , duration 1 month

TearB

Group Type EXPERIMENTAL

sodium hyaluronate

Intervention Type DRUG

QID to every 2 hous, 1-2 drops per each time, duration 1 month

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

hydroxypropylmethylcellulose

TearA: QID to every 2 hous , 1-2 drops per each time , duration 1 month

Intervention Type DRUG

sodium hyaluronate

QID to every 2 hous, 1-2 drops per each time, duration 1 month

Intervention Type DRUG

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* OSDI \> or equal 20 and eye lid inflammation , meibomian gland inflammation,conjunctival injection,follicle at tarsus , positive corneal staining , tear break up time less than 8 seconds , tear volume less than 5.5 mm.

Exclusion Criteria

* Age below 18 yo
* Active infectious corneal disease
* Post penetrating keratoplasty or glaucoma drainage device
* Known allergy to medication
* Lactation , Pregnant
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Mahidol University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Department of Ophthalmology

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

AssocProf Pinnita Tanthuvanit, MD

Role: PRINCIPAL_INVESTIGATOR

Mahidol University

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Department of Ophthalmology , Siriraj Hospital

Bangkok, Bangkok, Thailand

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

Thailand

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

AssocProf Pinnita Tanthuvanit

Role: CONTACT

02-4198036

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

655/2553(EC4)

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Next Generation Rocklatan
NCT06441643 COMPLETED PHASE2
H-1337 Ophthalmic Solution Phase 1/2
NCT03452033 COMPLETED PHASE1/PHASE2