Preemptive Lung Impedance-guided Therapy of Evolving Acute Heart Failure in Acute Myocardial Infarction Patients

NCT ID: NCT01264159

Last Updated: 2020-06-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

70 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-01-01

Study Completion Date

2015-07-01

Brief Summary

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It is well known that 20-25% of patients hospitalized for acute myocardial infarction will develop acute heart failure during their hospitalization. Currently, the investigators have no reliable parameter for prediction of evolving acute heart failure in such a group of patients. As a result, the investigators have no way of preventing acute heart failure. Treatment of these patients only begins after appearance of clinical signs of acute heart failure. Lung impedance monitoring may be a good non-invasive parameter for prediction of evolving acute heart failure. This study will attempt to address whether preemptive lung impedence-guided therapy may prevent the development of overt acute heart failure and improve their clinical outcome.

Detailed Description

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Conditions

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Acute Heart Failure

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Control

Group Type PLACEBO_COMPARATOR

Usual treatment of patients with developing acute heart failure

Intervention Type OTHER

Lung impedence-guided treatment

Group Type ACTIVE_COMPARATOR

Lung impedence-guided therapy

Intervention Type DEVICE

Interventions

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Lung impedence-guided therapy

Intervention Type DEVICE

Usual treatment of patients with developing acute heart failure

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients hospitalized in the ICCU for acute myocardial infarction and developing acute heart failure during their hospitalization

Exclusion Criteria

* Patients with acute myocardial infarction with clinical and radiological signs of acute heart failure at admission
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hillel Yaffe Medical Center

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Hillel Yaffe Medical Center

Hadera, , Israel

Site Status

Countries

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Israel

Other Identifiers

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0090-10-HYMC

Identifier Type: -

Identifier Source: org_study_id

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