Differential Diagnosis for the Causes of Subclavian Steal for Patients With Vascular Access in the Forearm

NCT ID: NCT01263301

Last Updated: 2013-02-12

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 16 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2010-08-31
• Study Completion Date: 2011-07-31

Brief Summary

Subclavian steal phenomenon is normally observed in patients with stenosis of subclavian artery proximal to orifice of vertebral artery(V0). However, uremic patients undergoing hemodialysis using vascular access in the arm or forearm may also develop dialysis associated steal syndrome(DASS).For patients with symptomatic subclavian steal phenomenon, the treatment for these two groups is different. The investigators want to see if the investigators can use noninvasive duplex examination instead of invasive conventional angiography to do the differential diagnosis.

Detailed Description

Carotid duplex is widely used for diagnosis of subclavian steal syndrome. We have a patient who suffered from acute brain stem stroke after receiving hemodialysis for months. He has DM related uremia and the vascular access is in the forearm. Subclavian steal was found on duplex in the same arm for hemodialysis. We used standard cuff test for diagnosis of subclavian steal by carotid duplex examination. Accidentally, we found the flow of subclavian artery was back to normal when the cuff is on that stops the flow. We want to see if this phenomenon can be used to serve as a differential diagnostic tool for differentiation of subclavian steal caused by stenosis of subclavian artery or due to DASS.

Conditions

Subclavian Steal

Study Design

• Allocation Method: NON_RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: DIAGNOSTIC
• Blinding Strategy: NONE

Study Groups

carotid duplex for hemolytic patients wtih SSS

assigned intervention:carotid duplex

Group Type: ACTIVE_COMPARATOR

carotid duplex

Intervention Type: DEVICE

Carotid duplex in the differential diagnosis of subclavian steal syndrome due to Arteriovenous Hemodialysis access in the Ipsilateral arm

carotid duplex for nonhemolytic patients with SSS

Group Type: ACTIVE_COMPARATOR

carotid duplex

Intervention Type: DEVICE

Carotid duplex in the differential diagnosis of subclavian steal syndrome due to Arteriovenous Hemodialysis access in the Ipsilateral arm

Interventions

carotid duplex

Carotid duplex in the differential diagnosis of subclavian steal syndrome due to Arteriovenous Hemodialysis access in the Ipsilateral arm

Intervention Type: DEVICE

Other Intervention Names

steal syndrome

Eligibility Criteria

Inclusion Criteria

• patients who revealed subclavian steal in the duplex study

Exclusion Criteria

• patients who has vascular access in the arm instead of the forearm

• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Mennonite Christian Hospital

OTHER

Sponsor Role: lead

Responsible Party

Ling-Chih, Wu

doctor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

lingchih wu

Role: PRINCIPAL_INVESTIGATOR

Mennonite Christian Hospital

Locations

Mennonite Christial Hospital

Hualien City, Taiwan, Taiwan

Countries

Taiwan

Other Identifiers

10-06-024-ER

Identifier Type: -

Identifier Source: org_study_id