The Effect of Chewing Gum on Small Bowel Transit Time

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

122 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-09-30

Study Completion Date

2013-07-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study is to see if chewing sugarless chewing gum alters the time it takes for a capsule endoscopy to travel through the stomach and small bowel, and to see if more/less capsule endoscopes reach the large bowel.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

The Effectiveness of Chewing Gum in Influencing Capsule Endoscopy Transit Time

NCT03815136

Gastric Transit Time Small-bowel Transit Time

COMPLETED NA

Impact of Chewing Gum on Bowel Preparation in Patients Undergoing Colonoscopy

NCT07320989

Colon Cancer Screening

NOT_YET_RECRUITING NA

Effect of Gum Chewing on Bowel Cleansing Before Colonoscopy

NCT02507037

Bowel Preparation Scale Adenoma Detection Rate

COMPLETED PHASE4

Effectiveness of Gum Chewing on Polyethylene Glycol Related Intake Adherence, GI Side Effects and Bowel Preparation

NCT05328219

Colonoscopy

COMPLETED NA

The Effect of Sham Feeding on Small Bowel Transit Time in Patients Undergoing Capsule Endoscopy

NCT02353208

Slow Transit

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The subjects will include patients already referred to us for a capsule endoscopy (CE) in this unit. We have calculated how many patients we need from small bowel transit times from the last 100 patients who had a CE at our centre. We will include 122. These will be randomly divided into two groups. The patients (chew chewing gum) and the controls (do not chew chewing gum).

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Bowel Transit Times

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

SINGLE

Participants

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

1.

The subject group will chew sugarless chewing gum for a specific amount of time while undergoing capsule endoscopy.

Group Type ACTIVE_COMPARATOR

Trident sugarless chewing gum.

Intervention Type OTHER

Patients will be randomly divided into 2 groups, one subject group (these chew gum) and one control group (these do not chew gum). The subjects will have to chew Trident sugarless chewing gum for 20-30 minutes every 2 hours, all together 4 times at t=0 h, t=2, t=4 and t=6 h.

2.

The control group will not chew chewing gum while undergoing capsule endoscopy.

Group Type PLACEBO_COMPARATOR

One control group (these do not chew gum).

Intervention Type OTHER

The control group will not chew chewing gum while undergoing capsule endoscopy

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Trident sugarless chewing gum.

Patients will be randomly divided into 2 groups, one subject group (these chew gum) and one control group (these do not chew gum). The subjects will have to chew Trident sugarless chewing gum for 20-30 minutes every 2 hours, all together 4 times at t=0 h, t=2, t=4 and t=6 h.

Intervention Type OTHER

One control group (these do not chew gum).

The control group will not chew chewing gum while undergoing capsule endoscopy

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* All out-patients \> 19 years old presenting for capsule endoscopy

Exclusion Criteria

* Patients on narcotics
* Patients on motility enhancing and/or slowing drugs should stop these at least 5 days prior to the procedure or be excluded from the study.
* Patients, who have proven or suspected obstruction of the bowel.
* Patients, who have had prior small bowel and/or gastric surgery.
* Patients with an ileostomy.
* Patients who have a known and/or have a history of swallowing disorder
* Patients with diabetes and/or hypo-/hyper- thyroidism
* Patients in whom the capsule become impacted at a stricture (these patients will be taken out of the study and given the necessary medical/surgical treatment).

Minimum Eligible Age

19 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No