Physiological Response to Exercise: Sensor Evaluation at Specified Exertions

NCT ID: NCT01229137

Last Updated: 2012-09-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

71 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-06-30

Study Completion Date

2012-08-31

Brief Summary

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Assessment of sensor parameter in patients with heart failure.

Detailed Description

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Evaluate the correlation of specific sensor parameters with clinical reference measurements in patients with heart failure.

Conditions

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Heart Failure

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Right Ventricular Cohort

Right Ventricle wtih SRD-1 conversion

SRD-1 conversion

Intervention Type DEVICE

Left Ventricular Cohort

Left Ventricle with SRD-1 conversion

SRD-1 conversion

Intervention Type DEVICE

Right Atrium Cohart

Right atrium cohort with SRD-1 conversion

SRD-1 conversion

Intervention Type DEVICE

Interventions

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SRD-1 conversion

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* COGNIS CRT-D model N119 or N120, functional bipolar leads: RA, RV, and LV lead all implanted for a minimum of 30 days
* Prescribed to optimal pharmacologic therapy for heart failure for at least 30 days prior to enrollment
* Age 18 or above, or of legal age to give informed consent specific to state and national law

Exclusion Criteria

* Documented HF decompensation, as defined by a hospitalization or greater than a doubling of baseline diuretic dose due to worsening HF, within the last 3 months
* Patients who are pacemaker dependent
* Creatinine ≥ 2.5 mg/dL test within the last 3 months
* Requires assistance walking, for example a cane or walker
* Have an atrial tachyarrhythmia that is permanent or persistent
* Have moderate to severe chronic pulmonary disease as defined by FEV1 \< 55% predicted
* Documented life expectancy of less than 6 months
* Patients at an unreasonable risk of not being able to reach the investigational center in case of an emergency, per physician discretion
* Enrolled in any concurrent study
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Boston Scientific Corporation

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Alan Bank, M.D.

Role: PRINCIPAL_INVESTIGATOR

United Heart and Vascular Center

Locations

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Cardiovascular Associates of Northeast Arkansas

Jonesboro, Arkansas, United States

Site Status

Regional Cardiology Consultants

Sacremento, California, United States

Site Status

Danbury Hospital

Danbury, Connecticut, United States

Site Status

Heart and Vascular Institute of Florida

Clearwater, Florida, United States

Site Status

Genesis Medical Center

Davenport, Iowa, United States

Site Status

University of Massachusetts Memorial Medical Center

Worcester, Massachusetts, United States

Site Status

St. John's Hospital and Medical Center

Detroit, Michigan, United States

Site Status

United Heart and Vascular Clinic

Saint Paul, Minnesota, United States

Site Status

Hackensack University Medical Center

Hackensack, New Jersey, United States

Site Status

Cardiovascular Research Institure, LLC

Canton, Ohio, United States

Site Status

Texas Cardiac Arrhythmia Research

Austin, Texas, United States

Site Status

Tyler Cardiovascular Associates

Tyler, Texas, United States

Site Status

Thomas Bunch

Murray, Utah, United States

Site Status

University of Virginia Medical Center

Charlottesville, Virginia, United States

Site Status

Countries

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United States

Other Identifiers

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G100110

Identifier Type: OTHER

Identifier Source: secondary_id

PRE-SENSE

Identifier Type: -

Identifier Source: org_study_id