Physiological Brain Atlas Development

NCT ID: NCT01210534

Last Updated: 2023-02-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

456 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-08-31

Study Completion Date

2021-10-18

Brief Summary

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Enrollment of candidates undergoing a deep brain stimulator (DBS) implant.

Detailed Description

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The study proposes the enrollment of candidates undergoing a deep brain stimulator (DBS) implant. Data will be collected before, during and after surgery and will be electronically entered into the Atlas database where it will be stored indefinitely.

The purpose of the study is to create an Atlas to store physiological information utilizing non-rigid MRI normalization algorithms. In addition to collating and analyzing the physiological atlas in a statistical manner that allows the surgeon to predict optimal targeting locations for DBS implants based on multiple physiological variables, including pre-operative severity of disease, intraoperative neurophysiological observations, and post-operative response to DBS stimulation therapy.

Conditions

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Parkinson Disease Dystonia Tremors Obsessive Compulsive Disorder Depression

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Interventions

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No intervention

No intervention

Intervention Type OTHER

Other Intervention Names

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Single Arm Group

Eligibility Criteria

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Inclusion Criteria

* Any patient between the age of 7-90
* Patients who have undergone deep brain stimulation (DBS) surgery as standard of care at The Ohio State University

Exclusion Criteria

* None
Minimum Eligible Age

7 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ohio State University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Vibhor Krishna, MD

Role: PRINCIPAL_INVESTIGATOR

Ohio State University

Locations

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The Ohio Sate University

Columbus, Ohio, United States

Site Status

Countries

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United States

Other Identifiers

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2010H0036

Identifier Type: -

Identifier Source: org_study_id

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