Percutaneous Treatment of LONG Native Coronary Lesions With Drug-Eluting Stent-IV: (LONG-DES-IV)
NCT ID: NCT01186094
Last Updated: 2012-08-08
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE4
502 participants
INTERVENTIONAL
2009-05-31
2011-06-30
Brief Summary
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Detailed Description
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Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Cypher
Sirolimus-eluting stent
Cypher
Sirolimus-eluting stent
Endeavor Resolute
Zotarolimus-eluting Stent
Endeavor Resolute
Zotarolimus-eluting Stent
Interventions
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Cypher
Sirolimus-eluting stent
Endeavor Resolute
Zotarolimus-eluting Stent
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Significant native coronary artery stenosis (\>50% by visual estimate) with lesion length of more than 25mm, which requiring single or multiple long stent placement (\>=28mm)
* Patients with silent ischemia, stable or unstable angina pectoris, ad Non-ST-elevation myocardial infarction
* The patient or guardian agrees to the study protocol and the schedule of clinical and angiographic follow-up, and provides informed, written consent, as approved by the appropriate Institutional Review Board/Ethical Committee of the respective clinical site.
Exclusion Criteria
* An elective surgical procedure is planned that would necessitate interruption of antiplatelet drugs during the first 6 months post enrollment.
* Acute ST-segment-elevation MI or cardiogenic shock
* Terminal illness with life expectancy \<1 year
* Patients who are actively participating in another drug or device investigational study, which have not completed the primary endpoint follow-up period.
* In-stent restenosis at target vessel (either bare metal stent or drug-eluting stent segment, non-target vessel ISR is permitted)
* Patients with EF\<30%.
* Serum creatinine level \>=3.0mg/dL or dependence on dialysis.
* Patients with left main stem stenosis (\>50% by visual estimate).
18 Years
ALL
No
Sponsors
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CardioVascular Research Foundation, Korea
OTHER
Medtronic
INDUSTRY
Seung-Jung Park
OTHER
Responsible Party
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Seung-Jung Park
MD,PhD, Chairman,Heart Institute, Asan Medical Center,University of Ulsan,College of Medicine
Principal Investigators
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Seung-Jung Park, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine
Locations
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Stcarollo Hospital
Suncheon, Cheon-nam, South Korea
Konyang University Hospital
Daejeon, Chungcheongnam-do, South Korea
Wonju Christian Hospital
Wŏnju, Gangwon-do, South Korea
Soon Chun Hyang University Hospital Bucheon
Bucheon-si, Gyeonggi-do, South Korea
Inje University Ilsan Paik Hospital
Ilsan, Gyeonggi-do, South Korea
Yeungnam University Medical Center
Daegu, Kyung-book, South Korea
Busan Paik Hospital
Busan, , South Korea
Dong-A University Medical Center
Busan, , South Korea
Soonchunhyang University Cheonan Hospital
Cheonan, , South Korea
Gangwon National University Hospital
Chuncheon, , South Korea
Asan Medical Center
Seoul, , South Korea
Kyung Hee University Medical Hospital
Seoul, , South Korea
Countries
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References
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Ahn JM, Park DW, Kim YH, Song H, Cho YR, Kim WJ, Lee JY, Kang SJ, Lee SW, Lee CW, Park SW, Yun SC, Han S, Lee SY, Lee BK, Cho JH, Yang TH, Lee NH, Yang JY, Park JS, Shin WY, Kim MH, Bae JH, Kim MK, Yoon J, Park SJ. Comparison of resolute zotarolimus-eluting stents and sirolimus-eluting stents in patients with de novo long coronary artery lesions: a randomized LONG-DES IV trial. Circ Cardiovasc Interv. 2012 Oct;5(5):633-40. doi: 10.1161/CIRCINTERVENTIONS.111.965673. Epub 2012 Oct 9.
Other Identifiers
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2008-0086
Identifier Type: -
Identifier Source: org_study_id