Tissue Doppler Imaging (TDI) Versus Electrocardiography (ECG) Interventricular Pacing Delay Optimization in Cardiac Resynchronization Therapy (CRT)

NCT ID: NCT01179997

Last Updated: 2014-02-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

156 participants

Study Classification

INTERVENTIONAL

Brief Summary

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The aim of this study was to compare the response to cardiac resynchronization therapy when the interventricular pacing interval was optimized by Tissue Doppler Imaging (TDI) to response when it was optimized following QRS width criteria.

Detailed Description

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Conditions

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Heart Failure Cardiac Resynchronization Therapy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Tissue Doppler Imaging (TDI) optimization

Interventricular pacing delay optimized according to Tissue-Doppler echocardiography

Group Type ACTIVE_COMPARATOR

Interventricular pacing delay optimization by using Tissue Doppler-derived displacement curves

Intervention Type DEVICE

Electrocardiographic optimization

Interventricular pacing delay optimized according to QRS width observation in the 12-lead surface electrocardiogram

Group Type ACTIVE_COMPARATOR

Electrocardiographic optimization of the interventricular pacing delay according to QRS width

Intervention Type DEVICE

Interventions

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Interventricular pacing delay optimization by using Tissue Doppler-derived displacement curves

Intervention Type DEVICE

Electrocardiographic optimization of the interventricular pacing delay according to QRS width

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patients submitted to de novo implant due to conventional cardiac resynchronization therapy indications.

Exclusion Criteria

\-
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Fundacio Clinic Barcelona

OTHER

Sponsor Role collaborator

Hospital Clinic of Barcelona

OTHER

Sponsor Role lead

Responsible Party

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Josep Lluis Mont Girbau

MD PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Hospital Clinic Universitari

Barcelona, Catalonia, Spain

Site Status

Countries

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Spain

Other Identifiers

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CRT-opt

Identifier Type: -

Identifier Source: org_study_id

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