The Effect of Nicardipine on Kidney Function During Orthognathic Surgery Under Hypotensive Anesthesia

NCT ID: NCT01175746

Last Updated: 2013-06-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

46 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-08-31

Study Completion Date

2011-12-31

Brief Summary

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Since nicardipine is known to protect kidney function, nicardipine infusion will result in better renal parameters measured in this study.

Detailed Description

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Conditions

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Healthy Subjects

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

TRIPLE

Participants Caregivers Investigators

Study Groups

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nicardipine

Group Type EXPERIMENTAL

Nicardipine

Intervention Type DRUG

remifentanil

Group Type ACTIVE_COMPARATOR

remifentanil

Intervention Type DRUG

0.1-0.5 ugkg/min during hypotensive anesthesia

Interventions

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Nicardipine

Intervention Type DRUG

remifentanil

0.1-0.5 ugkg/min during hypotensive anesthesia

Intervention Type DRUG

Other Intervention Names

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ultiva®

Eligibility Criteria

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Inclusion Criteria

* healthy adult patients undergoing hypotensive anesthesia

Exclusion Criteria

* patients with any co-morbidity
Minimum Eligible Age

20 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Yonsei University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Ji Young Kim

Role: PRINCIPAL_INVESTIGATOR

Severance hospital, YUHS

Other Identifiers

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3-2009-0196

Identifier Type: -

Identifier Source: org_study_id

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