Subjective Comfort With Multipurpose and Hydrogen Peroxide Lens Care Solutions in Soft Contact Lens Wearers

NCT ID: NCT01164865

Last Updated: 2012-10-12

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

View full results

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

78 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-06-30

Study Completion Date

2010-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study was to assess comfort in soft contact lens wearers.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Contact Lens Wear

Keywords

Explore important study keywords that can help with search, categorization, and topic discovery.

Soft Contact lens Multi-Purpose Solution Hydrogen Peroxide

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

OPTI-FREE RepleniSH

OPTI-FREE RepleniSH multipurpose disinfecting solution used with study contact lenses on a daily basis for 2 weeks.

Group Type EXPERIMENTAL

OPTI-FREE RepleniSH multipurpose disinfecting solution

Intervention Type DEVICE

FDA-approved, multipurpose disinfecting solution used according to provided instructions for cleaning, rinsing, storing, and disinfecting study contact lenses on a daily basis, 2 weeks.

Contact lenses

Intervention Type DEVICE

Contact lenses per subject's habitual brand and prescription worn every day for the duration of the study, 14 days, on a daily wear basis without scheduled replacement.

Clear Care

Clear Care contact lens care system used with study contact lenses on a daily basis for 2 weeks.

Group Type ACTIVE_COMPARATOR

Clear Care contact lens care system

Intervention Type DEVICE

FDA-approved, hydrogen peroxide-based, lens care system used according to provided instructions for cleaning, disinfecting, daily protein removing, and storage of study contact lenses on a daily basis, 2 weeks.

Contact lenses

Intervention Type DEVICE

Contact lenses per subject's habitual brand and prescription worn every day for the duration of the study, 14 days, on a daily wear basis without scheduled replacement.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

OPTI-FREE RepleniSH multipurpose disinfecting solution

FDA-approved, multipurpose disinfecting solution used according to provided instructions for cleaning, rinsing, storing, and disinfecting study contact lenses on a daily basis, 2 weeks.

Intervention Type DEVICE

Clear Care contact lens care system

FDA-approved, hydrogen peroxide-based, lens care system used according to provided instructions for cleaning, disinfecting, daily protein removing, and storage of study contact lenses on a daily basis, 2 weeks.

Intervention Type DEVICE

Contact lenses

Contact lenses per subject's habitual brand and prescription worn every day for the duration of the study, 14 days, on a daily wear basis without scheduled replacement.

Intervention Type DEVICE

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

OPTI-FREE® RepleniSH® Clear Care®

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Wear silicone hydrogel contact lenses on a daily wear basis;
* Currently using OPTI-FREE RepleniSH contact lens solution;
* Report comfort above 75 on a Visual Analog Scale at the Baseline Visit;
* Read, sign, and date IRB-approved informed consent and the privacy document;
* Be generally healthy and have normal ocular health;
* Be be willing to follow the study procedures and visit schedule;

Exclusion Criteria

* Use of additional lens cleaners;
* Known sensitivity to any ingredient in either of the test articles;
* Systemic or ocular disease or disorder (except refractive error) that would negatively affect the conduct or outcome of the study;
* Prior (within 7 days of enrollment) or current ocular infections;
* Clinically significant lash or lid abnormality;
* History of ocular surgery/trauma within the last 6 months;
* Use of any topical ocular or systemic antibiotics or corticosteroids within 7 days of enrollment;
* Participation in any other ophthalmic drug or device clinical trial within 30 days of enrollment;
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Alcon Research

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Countries

Review the countries where the study has at least one active or historical site.

United States

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

SMA-09-58

Identifier Type: -

Identifier Source: org_study_id