The Effects of Spirulina Platensis on Insulin Resistance in HIV-infected Patients
NCT ID: NCT01141777
Last Updated: 2011-01-04
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
33 participants
INTERVENTIONAL
2008-10-31
2009-02-28
Brief Summary
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Detailed Description
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Spirulina, has recently drawn attention on its cholesterol and blood pressure lowering effects, including improvement of glycaemic control in diabetics subjects, suggesting it can have some effects on insulin sensitivity.
The aim of this three month, experimental, prospective, randomised trial was to evaluate the effect of Spirulina on HIV/HAART-associated insulin resistance on 33 subjects. Primary outcome was change in insulin sensitivity during the trial, over two time periods; t=0 and t=12 weeks. The second objective was to compare between the two groups, the percentage of subjects who improved insulin sensitivity by the end of the study.
Recruitment started in October 2008 and the trial ended in February 2009.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
SUPPORTIVE_CARE
DOUBLE
Study Groups
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Spirulina platensis
Spirulina platensis
Subjects received 19g daily of supplement averagely.This was supplied as powder daily, in packs that lasted for 2weeks each. Each subject was therefore seen every two week to obtain new stock of supplements and evaluate compliance
Soya bean
Soya bean
Each subject received 19g of supplement on average daily. Subjects were seen every two weeks to evaluate compliance and obtain a new stock.
Interventions
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Spirulina platensis
Subjects received 19g daily of supplement averagely.This was supplied as powder daily, in packs that lasted for 2weeks each. Each subject was therefore seen every two week to obtain new stock of supplements and evaluate compliance
Soya bean
Each subject received 19g of supplement on average daily. Subjects were seen every two weeks to evaluate compliance and obtain a new stock.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Accepted to participate in the study
Exclusion Criteria
* Treatment that modifies glucose or lipid profile
* Pregnancy
* Known diabetic patient
* Chronic renal failure with calculated creatinine clearance \< 60ml/min
21 Years
ALL
No
Sponsors
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University of Yaounde
OTHER
Antenna Technologies
UNKNOWN
Yaounde Central Hospital
OTHER_GOV
Responsible Party
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Consultant Endocrinologist and Senior Lecturer, University of Yaounde 1, Cameroon and Newcastle University, UK
Principal Investigators
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Pr Jean Claude Mbanya, MD, PhD
Role: STUDY_DIRECTOR
International diabetes federation/ Director, National Obesity Centre, Yaounde Central Hospital, Cameroon
Dr Sobngwi Eugene, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
Consultant Endocrinologist, National Obesity Centre/ Senior Lecturer, University of Yaounde 1, Cameroon and Newcastle University, UK
Dr Marcel Azabji Kenfack, MD
Role: STUDY_CHAIR
Dep. of Physiologie, Faculty of Medicine and Biomedical Sciences University Yaoundé I, Cameroon
Dr Gabriel Loni Ekali, MD
Role: PRINCIPAL_INVESTIGATOR
National Obesity Centre, Yaounde Central Hospital, Cameroon
Locations
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National Obesity Centre, Yaounde Central Hospital
Yaoundé, Centre Region, Cameroon
Countries
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References
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Marcel AK, Ekali LG, Eugene S, Arnold OE, Sandrine ED, von der Weid D, Gbaguidi E, Ngogang J, Mbanya JC. The effect of Spirulina platensis versus soybean on insulin resistance in HIV-infected patients: a randomized pilot study. Nutrients. 2011 Jul;3(7):712-24. doi: 10.3390/nu3070712. Epub 2011 Jul 18.
Related Links
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MedlinePlus
U.S FDA Resources
Other Identifiers
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MAK-GLE_Spirulina
Identifier Type: -
Identifier Source: org_study_id
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