Control of MRSA in Nursing Homes: Decolonization vs Standard Precautions

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

157 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-06-30

Study Completion Date

2011-12-31

Brief Summary

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The purpose of this study is to determine the better approach between the currently procedure (i.e. standards precautions) and a reinforced strategy to control MRSA transmission in the institutionalized population of nursing homes in Canton of Vaud, Switzerland.

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Detailed Description

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MRSA carriage among nursing homes residents of Canton Vaud, Switzerland, is increasing, despite use of standard precautions. Recommendation to prevent MRSA transmission in long term care facilities are lacking. We aim to reinforce the current infection control strategy by general MRSA screening of institutionalised residents and decolonisation of MRSA carriers. Because the uncertainties in the impact of this reinforced strategy, we aim to compare this action to the policy actually applied.

Conditions

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Methicillin-Resistant Staphylococcus Aureus

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Standard Precautions

control arm, standards precautions for all residents living in the nursing home of control arm, including MRSA carriers

Group Type NO_INTERVENTION

No interventions assigned to this group

Intervention

Intervention arm, standards precautions for all residents living in nursing homes of intervention arm, and topical decolonization for MRSA carriers, including environmental disinfection

Group Type OTHER

intervention

Intervention Type OTHER

5 days topical decolonisation including nasal mupirocin tid, chlorhexidine mouth wash tid, chlorhexidine body wash once daily.

Daily direct resident's environmental disinfection during decolonisation.

Interventions

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intervention

5 days topical decolonisation including nasal mupirocin tid, chlorhexidine mouth wash tid, chlorhexidine body wash once daily.

Daily direct resident's environmental disinfection during decolonisation.

Intervention Type OTHER

Other Intervention Names

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topical MRSA decolonisation and environmental disinfection

Eligibility Criteria

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Inclusion Criteria

* all nursing homes of canton Vaud, Switzerland, that give the consent of participation

\- all MRSA positive residents living in a Nursing Home included in the intervention group

Exclusion Criteria

\- refusal to participate

* residents that refuse to be screened or refused the decolonisation
* life expectancy shorter of 7 days
* known intolerance of disinfectant/ topical antibiotics used in the protocol
* active MRSA infection
* asymptomatic MRSA bacteriuria
* stage IV wound (according to National Pressure Ulcer Advisory Panel)

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes